The cDNA sequence and the deduced amino acid sequence of human transcobalamin II show homology with rat intrinsic factor and human transcobalamin I

The cellular uptake of cobalamin (Cbl, vitamin B12) is mediated by transcobalamin II (TCII), a plasma protein that binds Cbl and is secreted by human umbilical vein endothelial (HUVE) cells. These cells synthesize and secrete TCII and, therefore, served as the source of the complementary DNA (cDNA)...

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Veröffentlicht in:	The Journal of biological chemistry 1991-04, Vol.266 (12), p.7860-7863
Hauptverfasser:	Platica, O, Janeczko, R, Quadros, E V, Regec, A, Romain, R, Rothenberg, S P
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Blotting, Northern DNA - genetics endothelium genes Humans Intrinsic Factor - genetics Molecular Sequence Data Poly A - analysis Rats Restriction Mapping RNA - analysis Sequence Homology, Nucleic Acid Transcobalamins - genetics umbilical vein
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