Synthesis of 5-nitro-2-[N-3-(4-azidophenyl)-propylamino]-benzoic acid: Photoaffinity labeling of human red blood cell ghosts with A 5-nitro-2-(3-phenylpropylamino)-benzoic acid analog

A photoaffinity analog of the potent epithelial chloride channel blocker 5-nitro-2-(3-phenylpropylamino)-benzoic acid has been synthesized and characterized. In the dark, this reagent, 5-nitro-2-[N-3-(4-azidophenyl)-propylamino]-benzoic acid, and the parent compound reversibly inhibited chloride eff...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 1991-04, Vol.176 (1), p.459-465
Hauptverfasser:	Branchini, Bruce R., Murtiashaw, Martha H., Egan, Laura A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Labels - chemical synthesis Azides - chemical synthesis Azides - pharmacology Biological and medical sciences Chlorides - blood Darkness Diverse techniques Erythrocyte Membrane - drug effects Erythrocyte Membrane - metabolism Erythrocyte Membrane - radiation effects Fundamental and applied biological sciences. Psychology Humans Indicators and Reagents Kinetics Light Magnetic Resonance Spectroscopy Mass Spectrometry Molecular and cellular biology Molecular Structure Nitrobenzoates - chemical synthesis Nitrobenzoates - pharmacology Spectrophotometry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!