Oxidation of cholesterol moiety of low density lipoprotein in the presence of human endothelial cells or Cu +2 ions: Identification of major products and their effects

Oxidation of lipoproteins is believed to play a key role in atherogenesis. In this study, low density lipoproteins (LDL) was subjected to oxidation in the presence of either human umbilical vein endothelial cells or with Cu +2 ions and the major oxides formed were identified. While cholesterol-α-epo...

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