Examination of the role of catecholamines in hepatic glutathione suppression by cold-restraint in mice

Cold-restraint stress was found to produce a depression in hepatic glutathione content and to elevate circulating catecholamine levels in four mouse strains--ICR, NIH, B6C3F1, and ND/4. Serum norepinephrine concentrations were significantly elevated after cold-restraint (2--3 h) in all strains, and...

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Veröffentlicht in:	Toxicology (Amsterdam) 1991-03, Vol.67 (1), p.29-40
Hauptverfasser:	SIMMONS, H. F, JAMES, R. C, HARBISON, R. D, PATEL, D. G, ROBERTS, S. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Temperature Catecholamines - blood Catecholamines - metabolism Cold Temperature - adverse effects Epinephrine - blood Epinephrine - metabolism Epinephrine - pharmacology General aspects. Methods Glucagon - pharmacology Glutathione - metabolism Hydrocortisone - pharmacology Liver - metabolism Male Medical sciences Mice Mice, Inbred ICR Mice, Inbred Strains Norepinephrine - blood Norepinephrine - metabolism Phentolamine - pharmacology Propranolol - pharmacology Stress, Physiological - metabolism Toxicology
Online-Zugang:	Volltext
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