A myristylated form of the sea oncoprotein can transform chicken embryo fibroblasts

The transforming gene product of the S13 avian erythroblastosis virus, v-sea, is a member of the growth factor receptor class of tyrosine kinases. In the virus genome, the sea sequences are fused in frame to the virus env gene, thereby generating an abnormally large envelope protein because of the p...

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Veröffentlicht in:	Journal of Virology 1991-05, Vol.65 (5), p.2533-2538
Hauptverfasser:	Crowe, A.J. (State University of New York at Stony Brook, Stony Brook, NY), Hayman, M.J
Format:	Artikel
Sprache:	eng
Schlagworte:	ACIDE MYRISTIQUE ACIDO MIRISTICO Animals avian erythroblastosis virus Biological and medical sciences Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cell Transformation, Neoplastic Cell Transformation, Viral Cells, Cultured Chick Embryo Cloning, Molecular EMBRIONES ANIMALES EMBRYON ANIMAL FIBROBLASTE FIBROBLASTOS Fibroblasts FOSFORILACION Fundamental and applied biological sciences. Psychology GENE GENES Molecular and cellular biology Myristic Acids - metabolism NEOPLASMAS NEOPLASME Oncogene Proteins, Viral - metabolism PHOSPHORYLATION POLLITO POUSSIN Protein-Tyrosine Kinases - metabolism PROTEINA QUINASA PROTEINAS PROTEINE PROTEINE KINASE REACCIONES QUIMICAS REACTION CHIMIQUE Recombinant Fusion Proteins - metabolism RETROVIRIDAE Transfection VIRUS
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