Purification and Characterization of Hepatocyte Growth Factor from Injured Liver of Carbon Tetrachloride-Treated Rats

A hepatocyte growth factor (HGF)-like substance that strongly stimulated DNA synthesis of adult rat hepatocytes in primary culture was found to increase markedly in liver of rats treated with carbon tetrachloride (CCl4). This increase of HGF-like activity was time- and dose-dependent, and 36 h after...

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Veröffentlicht in:	Journal of biochemistry (Tokyo) 1991-01, Vol.109 (1), p.8-13
Hauptverfasser:	Asami, Osamu, Ihara, Izumi, Shimidzu, Norihide, Shimizu, Shin, Tomita, Yumiko, Ichihara, Akira, Nakamura, Toshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Carbon Tetrachloride DNA - biosynthesis Growth Substances - chemistry Growth Substances - isolation & purification Hepatocyte Growth Factor In Vitro Techniques liver Liver - drug effects Liver - injuries Liver - metabolism Molecular Sequence Data Molecular Weight Rats Rats, Inbred Strains RNA, Messenger - metabolism
Online-Zugang:	Volltext
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