Cyclosporin A modulates the course of woodchuck hepatitis virus infection and induces chronicity

Immunosuppression is known to influence the state of chronic hepatitis B virus infection, and is thought to increase the risk of developing chronic infection in newly exposed individuals. Cyclosporin A (CsA), an immunosuppressive agent that inhibits Th cell function, was administered to woodchucks c...

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Veröffentlicht in:	The Journal of immunology (1950) 1991-05, Vol.146 (9), p.3138-3144
Hauptverfasser:	Cote, PJ, Korba, BE, Steinberg, H, Ramirez-Mejia, C, Baldwin, B, Hornbuckle, WE, Tennant, BC, Gerin, JL
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Antigens, Viral - analysis Chronic Disease Cyclosporins - pharmacokinetics Cyclosporins - pharmacology DNA, Viral - analysis Hepadnaviridae - immunology Hepadnaviridae - pathogenicity Hepatitis, Viral, Animal - drug therapy Hepatitis, Viral, Animal - immunology Liver - pathology Marmota T-Lymphocytes, Helper-Inducer - immunology
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