Electrophysiologic effects of bretylium on canine ventricular muscle during acute ischemia and reperfusion

Electrophysiologic effects of bretylium were assessed on a recently developed animal model for analysis of conduction of premature impulses and excitation threshold. Bretylium was administered intravenously 10 mg/kg over 10 minutes followed by 2 mg/min of infusion immediately after coronary ligation...

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Veröffentlicht in:	The American heart journal 1983-06, Vol.105 (6), p.966-972
Hauptverfasser:	Fujimoto, Toshifumi, Hamamoto, Hiromu, Peter, Thomas, McCullen, Avile, McCullen, Antony, Melvin, Nancy, Mandel, William J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bretylium Compounds - pharmacology Bretylium Tosylate - blood Bretylium Tosylate - pharmacology Cardiac Pacing, Artificial Coronary Disease - blood Coronary Disease - complications Coronary Disease - physiopathology Dogs Electrophysiology Endocardium - innervation Heart Conduction System - physiopathology Male Pericardium - innervation Ventricular Fibrillation - complications Ventricular Fibrillation - physiopathology
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