In Vivo Platelet Activation in β-Thalassemia Major Reflected by Increased Platelet-Thromboxane Urinary Metabolites

Increased frequency of thromboembolic events has been recently observed in patients with β-thalassemia major (TM). Platelet function anomalies including impaired aggregation, increased circulating aggregates, and our finding of shortened platelet survival indicate that platelets may be involved in t...

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Veröffentlicht in:	Blood 1991-04, Vol.77 (8), p.1749-1753
Hauptverfasser:	Eldor, Amiram, Lellouche, Franck, Goldfarb, Ada, Rachmilewitz, E.A., Maclouf, Jacques
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Ketoprostaglandin F1 alpha - urine Adolescent Adult Aspirin - pharmacology Biological and medical sciences Female Hematologic and hematopoietic diseases Humans Male Medical sciences Platelet Activation Thalassemia - blood Thalassemia - urine Thromboxane B2 - blood Thromboxane B2 - urine
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