Quality Control of Albumin Solutions by Size-Exclusion High-Performance Liquid Chromatography, Isoelectric Focusing, and Two-Dimensional Immunoelectrophoresis

Quality control of albumin solutions for human use is of utmost importance because the presence of impurities can provoke adverse reactions in treated patients. Three different techniques were used to detect the presence of albumin oligomers and polymers as well as foreign proteins in commercial sol...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1991-01, Vol.80 (1), p.11-16
Hauptverfasser:	Van Liedekerke, Beatrijs M., Nelis, Hans J., Kint, Jos A., Vanneste, Franck W., De Leenheer, Andre P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumins - administration & dosage Analysis Biological and medical sciences Chromatography, High Pressure Liquid - methods General pharmacology Humans Immunoelectrophoresis, Two-Dimensional Isoelectric Focusing Medical sciences Molecular Weight Pharmacology. Drug treatments Quality Control Solutions - standards
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