Cinematographic Analysis of Vascular Smooth Muscle Cell Interactions with Extracellular Matrix
The interactions of vascular smooth muscle cells with growth modulators and extracellular matrix molecules may play a role in the proliferation and migration of these cells after vascular injury and during the development of atherosclerosis. Time-lapse cinematographic techniques have been used to st...
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| Veröffentlicht in: | In Vitro Cellular & Developmental Biology - Animal 1991-01, Vol.27A (1), p.25-30 |
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| container_title | In Vitro Cellular & Developmental Biology - Animal |
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| creator | ABSHER, M BALDOR, L |
| description | The interactions of vascular smooth muscle cells with growth modulators and extracellular matrix molecules may play a role in the proliferation and migration of these cells after vascular injury and during the development of atherosclerosis. Time-lapse cinematographic techniques have been used to study cell division and migration of bovine carotid artery smooth muscle cells in response to matrix molecules consisting of solubilized basement membrane (Matrigel) and type I collagen. When cells were grown adjacent to Matrigel, both migration and cell proliferation were increased and interdivision time was shortened. Cells grown in Matrigel or in type I collagen had markedly reduced migration rates but interdivision time was not altered. Further, diffusible components of the Matrigel were found to stimulate proliferation of the smooth muscle cells. |
| doi_str_mv | 10.1007/BF02630891 |
| format | Article |
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Time-lapse cinematographic techniques have been used to study cell division and migration of bovine carotid artery smooth muscle cells in response to matrix molecules consisting of solubilized basement membrane (Matrigel) and type I collagen. When cells were grown adjacent to Matrigel, both migration and cell proliferation were increased and interdivision time was shortened. Cells grown in Matrigel or in type I collagen had markedly reduced migration rates but interdivision time was not altered. Further, diffusible components of the Matrigel were found to stimulate proliferation of the smooth muscle cells.</description><identifier>ISSN: 0883-8364</identifier><identifier>EISSN: 2327-431X</identifier><identifier>EISSN: 1543-706X</identifier><identifier>DOI: 10.1007/BF02630891</identifier><identifier>PMID: 2013550</identifier><identifier>CODEN: ICDBEO</identifier><language>eng</language><publisher>Largo, MD: Tissue Culture Association, Inc</publisher><subject>Animals ; Basement Membrane - physiology ; binding ; Biocompatible Materials - pharmacology ; Biological and medical sciences ; blood vessels ; Carotid Arteries - cytology ; Carotid Arteries - physiology ; Cattle ; Cell cycle, cell proliferation ; Cell Division ; Cell growth ; Cell Movement - drug effects ; Cell physiology ; Cells, Cultured ; Cinematography ; Collagen - pharmacology ; Collagens ; Cultured cells ; Drug Combinations ; Endothelial cells ; Extracellular matrix ; Extracellular Matrix - physiology ; Extracellular Matrix - ultrastructure ; Fundamental and applied biological sciences. Psychology ; Gels ; Kinetics ; Laminin - pharmacology ; Molecular and cellular biology ; Motion Pictures ; Muscle, Smooth, Vascular - cytology ; Muscle, Smooth, Vascular - physiology ; Proteoglycans - pharmacology ; Siblings ; smooth muscle ; Smooth muscle myocytes ; Time Factors</subject><ispartof>In Vitro Cellular & Developmental Biology - Animal, 1991-01, Vol.27A (1), p.25-30</ispartof><rights>Copyright 1991 Tissue Culture Association</rights><rights>1993 INIST-CNRS</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c392t-f6411114adf8b4265a63ae9e44082f7437fe3629bfc1803fbe32d458ffc0e61f3</citedby><cites>FETCH-LOGICAL-c392t-f6411114adf8b4265a63ae9e44082f7437fe3629bfc1803fbe32d458ffc0e61f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/4296600$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/4296600$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,4024,27923,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4716051$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5261285$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2013550$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ABSHER, M</creatorcontrib><creatorcontrib>BALDOR, L</creatorcontrib><title>Cinematographic Analysis of Vascular Smooth Muscle Cell Interactions with Extracellular Matrix</title><title>In Vitro Cellular & Developmental Biology - Animal</title><addtitle>In Vitro Cell Dev Biol</addtitle><description>The interactions of vascular smooth muscle cells with growth modulators and extracellular matrix molecules may play a role in the proliferation and migration of these cells after vascular injury and during the development of atherosclerosis. Time-lapse cinematographic techniques have been used to study cell division and migration of bovine carotid artery smooth muscle cells in response to matrix molecules consisting of solubilized basement membrane (Matrigel) and type I collagen. When cells were grown adjacent to Matrigel, both migration and cell proliferation were increased and interdivision time was shortened. Cells grown in Matrigel or in type I collagen had markedly reduced migration rates but interdivision time was not altered. Further, diffusible components of the Matrigel were found to stimulate proliferation of the smooth muscle cells.</description><subject>Animals</subject><subject>Basement Membrane - physiology</subject><subject>binding</subject><subject>Biocompatible Materials - pharmacology</subject><subject>Biological and medical sciences</subject><subject>blood vessels</subject><subject>Carotid Arteries - cytology</subject><subject>Carotid Arteries - physiology</subject><subject>Cattle</subject><subject>Cell cycle, cell proliferation</subject><subject>Cell Division</subject><subject>Cell growth</subject><subject>Cell Movement - drug effects</subject><subject>Cell physiology</subject><subject>Cells, Cultured</subject><subject>Cinematography</subject><subject>Collagen - pharmacology</subject><subject>Collagens</subject><subject>Cultured cells</subject><subject>Drug Combinations</subject><subject>Endothelial cells</subject><subject>Extracellular matrix</subject><subject>Extracellular Matrix - physiology</subject><subject>Extracellular Matrix - ultrastructure</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gels</subject><subject>Kinetics</subject><subject>Laminin - pharmacology</subject><subject>Molecular and cellular biology</subject><subject>Motion Pictures</subject><subject>Muscle, Smooth, Vascular - cytology</subject><subject>Muscle, Smooth, Vascular - physiology</subject><subject>Proteoglycans - pharmacology</subject><subject>Siblings</subject><subject>smooth muscle</subject><subject>Smooth muscle myocytes</subject><subject>Time Factors</subject><issn>0883-8364</issn><issn>2327-431X</issn><issn>1543-706X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtLLDEQRoNc0fGxuet7oRfiQmitPDu9HAdfoLjwgSubTCbRSHdnTNKo_96MM-jSbApyTlWFLwj9xXCIAaqj41MggoKs8RoaEUqqklH88AeNQEpaSirYJtqK8QWAgiBkA20QwJRzGKHHietNp5J_Cmr-7HQx7lX7EV0svC3uVdRDq0Jx03mfnourIerWFBPTtsVFn0xQOjnfx-LNZXrynvJFZl8tVyoF976D1q1qo9ld1W10d3pyOzkvL6_PLibjy1LTmqTSCobzYWpm5ZQRwZWgytSGMZDEVoxW1lBB6qnVWAK1U0PJjHFprQYjsKXbaH85dx7862BiajoXF29RvfFDbCRwYLgWv4pYCEYJ4Vk8WIo6-BiDsc08uE6FjwZDs0i9-Uk9y_9XU4dpZ2bf6irmzPdWPCeqWhtUr1381jgRmEj-m8YqLIAvtv1bai8x-fCDSS1E_uJPz7efFw</recordid><startdate>19910101</startdate><enddate>19910101</enddate><creator>ABSHER, M</creator><creator>BALDOR, L</creator><general>Tissue Culture Association, Inc</general><general>Society for In Vitro Biology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19910101</creationdate><title>Cinematographic Analysis of Vascular Smooth Muscle Cell Interactions with Extracellular Matrix</title><author>ABSHER, M ; BALDOR, L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c392t-f6411114adf8b4265a63ae9e44082f7437fe3629bfc1803fbe32d458ffc0e61f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Animals</topic><topic>Basement Membrane - physiology</topic><topic>binding</topic><topic>Biocompatible Materials - pharmacology</topic><topic>Biological and medical sciences</topic><topic>blood vessels</topic><topic>Carotid Arteries - cytology</topic><topic>Carotid Arteries - physiology</topic><topic>Cattle</topic><topic>Cell cycle, cell proliferation</topic><topic>Cell Division</topic><topic>Cell growth</topic><topic>Cell Movement - drug effects</topic><topic>Cell physiology</topic><topic>Cells, Cultured</topic><topic>Cinematography</topic><topic>Collagen - pharmacology</topic><topic>Collagens</topic><topic>Cultured cells</topic><topic>Drug Combinations</topic><topic>Endothelial cells</topic><topic>Extracellular matrix</topic><topic>Extracellular Matrix - physiology</topic><topic>Extracellular Matrix - ultrastructure</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gels</topic><topic>Kinetics</topic><topic>Laminin - pharmacology</topic><topic>Molecular and cellular biology</topic><topic>Motion Pictures</topic><topic>Muscle, Smooth, Vascular - cytology</topic><topic>Muscle, Smooth, Vascular - physiology</topic><topic>Proteoglycans - pharmacology</topic><topic>Siblings</topic><topic>smooth muscle</topic><topic>Smooth muscle myocytes</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ABSHER, M</creatorcontrib><creatorcontrib>BALDOR, L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>In Vitro Cellular & Developmental Biology - Animal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ABSHER, M</au><au>BALDOR, L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cinematographic Analysis of Vascular Smooth Muscle Cell Interactions with Extracellular Matrix</atitle><jtitle>In Vitro Cellular & Developmental Biology - Animal</jtitle><addtitle>In Vitro Cell Dev Biol</addtitle><date>1991-01-01</date><risdate>1991</risdate><volume>27A</volume><issue>1</issue><spage>25</spage><epage>30</epage><pages>25-30</pages><issn>0883-8364</issn><eissn>2327-431X</eissn><eissn>1543-706X</eissn><coden>ICDBEO</coden><abstract>The interactions of vascular smooth muscle cells with growth modulators and extracellular matrix molecules may play a role in the proliferation and migration of these cells after vascular injury and during the development of atherosclerosis. Time-lapse cinematographic techniques have been used to study cell division and migration of bovine carotid artery smooth muscle cells in response to matrix molecules consisting of solubilized basement membrane (Matrigel) and type I collagen. When cells were grown adjacent to Matrigel, both migration and cell proliferation were increased and interdivision time was shortened. Cells grown in Matrigel or in type I collagen had markedly reduced migration rates but interdivision time was not altered. Further, diffusible components of the Matrigel were found to stimulate proliferation of the smooth muscle cells.</abstract><cop>Largo, MD</cop><pub>Tissue Culture Association, Inc</pub><pmid>2013550</pmid><doi>10.1007/BF02630891</doi><tpages>6</tpages></addata></record> |
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| subjects | Animals Basement Membrane - physiology binding Biocompatible Materials - pharmacology Biological and medical sciences blood vessels Carotid Arteries - cytology Carotid Arteries - physiology Cattle Cell cycle, cell proliferation Cell Division Cell growth Cell Movement - drug effects Cell physiology Cells, Cultured Cinematography Collagen - pharmacology Collagens Cultured cells Drug Combinations Endothelial cells Extracellular matrix Extracellular Matrix - physiology Extracellular Matrix - ultrastructure Fundamental and applied biological sciences. Psychology Gels Kinetics Laminin - pharmacology Molecular and cellular biology Motion Pictures Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - physiology Proteoglycans - pharmacology Siblings smooth muscle Smooth muscle myocytes Time Factors |
| title | Cinematographic Analysis of Vascular Smooth Muscle Cell Interactions with Extracellular Matrix |
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