Modulation of cis-platinum resistance in friend erythroleukemia cells by c-myc

The molecular genetic basis for cancer cell resistance to the important family of platinum coordination complex drugs is poorly understood. The observation that malignant cells commonly become resistant to therapy, while normal cells rarely do, suggests that certain molecular processes involved in m...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1991-04, Vol.51 (8), p.2118-2123
Hauptverfasser:	SKLAR, M. D, PROCHOWNIK, E. V
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Cell Cycle Cell Line Cisplatin - metabolism Drug Resistance - genetics Friend murine leukemia virus Gene Amplification Gene Expression Regulation, Leukemic General aspects Genes, myc - genetics Leukemia, Erythroblastic, Acute - genetics Leukemia, Erythroblastic, Acute - metabolism Medical sciences Pharmacology. Drug treatments Transfection - genetics
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