Antitumor effects of interleukin 2 liposomes and anti-CD3-stimulated T-cells against murine MCA-38 hepatic metastasis

The stimulation of murine splenocytes with the monoclonal antibody anti-CD3 and interleukin 2 (IL-2) results in the propagation of large numbers of cells (T-activated killer; T-AK) which demonstrate high therapeutic efficacy when infused with IL-2 into mice bearing pulmonary metastases. Interleukin...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1991-04, Vol.51 (8), p.2127-2132
Hauptverfasser:	Loeffler, C M, Platt, J L, Anderson, P M, Katsanis, E, Ochoa, J B, Urba, W J, Longo, D L, Leonard, A S, Ochoa, A C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation, T-Lymphocyte - administration & dosage Antigens, Differentiation, T-Lymphocyte - pharmacology CD3 Complex Colonic Neoplasms Drug Carriers Interleukin-2 - administration & dosage Interleukin-2 - pharmacology Liposomes Liver Neoplasms - secondary Liver Neoplasms - therapy Lymphocytes, Tumor-Infiltrating Mice Mice, Inbred C57BL Receptors, Antigen, T-Cell - administration & dosage Receptors, Antigen, T-Cell - pharmacology T-Lymphocytes - immunology
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