Effects of lidocaine and droxicainide on myocardial necrosis: A comparative study

Lidocaine has been shown to protect ischemic myocardium, but the degree of its effectiveness is not yet well established. Therefore, in this study, the effects of this drug on ultimate infarct size were examined quantitatively. Another member of the same class of drugs, droxicainide (ALS1249), DL-N-...

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Veröffentlicht in:	J. Am. Coll. Cardiol.; (United States) 1983-06, Vol.1 (6), p.1447-1452
Hauptverfasser:	Faria, Duarte B., Cheung, Wai-Man, Ribeiro, Lair G.T., Maroko, Peter R.
Format:	Artikel
Sprache:	eng
Schlagworte:	550601 - Medicine- Unsealed Radionuclides in Diagnostics ANESTHETICS Anilides - therapeutic use ANIMALS Anti-Arrhythmia Agents - therapeutic use BIOLOGICAL EFFECTS Blood Pressure - drug effects BODY CARDIOVASCULAR DISEASES CARDIOVASCULAR SYSTEM CENTRAL NERVOUS SYSTEM DEPRESSANTS Coronary Disease - drug therapy Coronary Disease - pathology DIAGNOSTIC USES DISEASES DOGS DRUGS ELEMENTS HEART Heart Rate - drug effects ISCHEMIA Lidocaine - therapeutic use MAMMALS METALS Microspheres MUSCLES MYOCARDIAL INFARCTION MYOCARDIUM Myocardium - pathology NECROSIS ORGANS PATHOLOGICAL CHANGES RADIOLOGY AND NUCLEAR MEDICINE TECHNETIUM THERAPY TRANSITION ELEMENTS USES VASCULAR DISEASES VERTEBRATES
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