Determination of the anatomical size of ventricular septal defects on the basis of hemodynamic data and noninvasive assessment of pulmonary to systemic vascular resistance ratio rp/rs by doppler-echocardiography

The pulmonary and systemic flow (Qp/Qs) and resistance ratios (RP/Rs) were determined in children with isolated ventricular septal defects (VSD) to derive an “effective defect resistance” (Rd/Rs) representing the ratios of the resistance of the defect to the systemic vascular resistance. The defect...

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Veröffentlicht in:Catheterization and cardiovascular diagnosis 1991-02, Vol.22 (2), p.93-99
Hauptverfasser: Rupprecht, Thomas, Hofbeck, Michael, Singer, Helmut, Harms, Dieter, Deeg, Karl-Heinz, Benson, Lee
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container_issue 2
container_start_page 93
container_title Catheterization and cardiovascular diagnosis
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creator Rupprecht, Thomas
Hofbeck, Michael
Singer, Helmut
Harms, Dieter
Deeg, Karl-Heinz
Benson, Lee
description The pulmonary and systemic flow (Qp/Qs) and resistance ratios (RP/Rs) were determined in children with isolated ventricular septal defects (VSD) to derive an “effective defect resistance” (Rd/Rs) representing the ratios of the resistance of the defect to the systemic vascular resistance. The defect size (expressed as the ratio of the area of the defect to the cross‐sectional area of the ascending aorta) was related to the calculated “effective defect resistance,” where a significant (non‐linear) correlation was found. The effective resistance of the defect is a useful aid for estimation of the anatomical size of a ventricular septal defect. The close correlation between anatomical size and the hemodynamic parameter Rd/Rs allows one to calculate the ratio Rp/Rs with this concept using nonin‐vasive Doppler‐ultrasound and echocardiography. This was performed in 21 children with VSD who underwent cardiac catheterisation. The noninvasive calculated flow ratio Qp/Qs and the resistance ratio Rp/Rs showed a close correlation to the values measured at cardiac catheterisation.
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The defect size (expressed as the ratio of the area of the defect to the cross‐sectional area of the ascending aorta) was related to the calculated “effective defect resistance,” where a significant (non‐linear) correlation was found. The effective resistance of the defect is a useful aid for estimation of the anatomical size of a ventricular septal defect. The close correlation between anatomical size and the hemodynamic parameter Rd/Rs allows one to calculate the ratio Rp/Rs with this concept using nonin‐vasive Doppler‐ultrasound and echocardiography. This was performed in 21 children with VSD who underwent cardiac catheterisation. 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Malformations of the aorta, pulmonary vessels and vena cava ; echocardiography ; Echocardiography, Doppler ; effective defect resistance ; Female ; Heart ; Heart Septal Defects, Ventricular - diagnostic imaging ; Heart Septal Defects, Ventricular - pathology ; Hemodynamics - physiology ; Humans ; Infant ; Male ; Medical sciences ; Models, Cardiovascular ; Pulmonary Circulation - physiology ; Regression Analysis ; Vascular Resistance - physiology ; ventricular septal defect</subject><ispartof>Catheterization and cardiovascular diagnosis, 1991-02, Vol.22 (2), p.93-99</ispartof><rights>Copyright © 1991 John Wiley &amp; Sons, Ltd.</rights><rights>1991 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4085-30226b8a94591dd87fe2ff08f6a18746f99234ce5bdf3b936d6b0bb2840a5d853</citedby><cites>FETCH-LOGICAL-c4085-30226b8a94591dd87fe2ff08f6a18746f99234ce5bdf3b936d6b0bb2840a5d853</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fccd.1810220205$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fccd.1810220205$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=19770414$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2009570$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rupprecht, Thomas</creatorcontrib><creatorcontrib>Hofbeck, Michael</creatorcontrib><creatorcontrib>Singer, Helmut</creatorcontrib><creatorcontrib>Harms, Dieter</creatorcontrib><creatorcontrib>Deeg, Karl-Heinz</creatorcontrib><creatorcontrib>Benson, Lee</creatorcontrib><title>Determination of the anatomical size of ventricular septal defects on the basis of hemodynamic data and noninvasive assessment of pulmonary to systemic vascular resistance ratio rp/rs by doppler-echocardiography</title><title>Catheterization and cardiovascular diagnosis</title><addtitle>Cathet. Cardiovasc. Diagn</addtitle><description>The pulmonary and systemic flow (Qp/Qs) and resistance ratios (RP/Rs) were determined in children with isolated ventricular septal defects (VSD) to derive an “effective defect resistance” (Rd/Rs) representing the ratios of the resistance of the defect to the systemic vascular resistance. The defect size (expressed as the ratio of the area of the defect to the cross‐sectional area of the ascending aorta) was related to the calculated “effective defect resistance,” where a significant (non‐linear) correlation was found. The effective resistance of the defect is a useful aid for estimation of the anatomical size of a ventricular septal defect. The close correlation between anatomical size and the hemodynamic parameter Rd/Rs allows one to calculate the ratio Rp/Rs with this concept using nonin‐vasive Doppler‐ultrasound and echocardiography. This was performed in 21 children with VSD who underwent cardiac catheterisation. 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Vascular system</topic><topic>congenital heart disease</topic><topic>Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava</topic><topic>echocardiography</topic><topic>Echocardiography, Doppler</topic><topic>effective defect resistance</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Septal Defects, Ventricular - diagnostic imaging</topic><topic>Heart Septal Defects, Ventricular - pathology</topic><topic>Hemodynamics - physiology</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Models, Cardiovascular</topic><topic>Pulmonary Circulation - physiology</topic><topic>Regression Analysis</topic><topic>Vascular Resistance - physiology</topic><topic>ventricular septal defect</topic><toplevel>online_resources</toplevel><creatorcontrib>Rupprecht, Thomas</creatorcontrib><creatorcontrib>Hofbeck, Michael</creatorcontrib><creatorcontrib>Singer, Helmut</creatorcontrib><creatorcontrib>Harms, Dieter</creatorcontrib><creatorcontrib>Deeg, Karl-Heinz</creatorcontrib><creatorcontrib>Benson, Lee</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Catheterization and cardiovascular diagnosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rupprecht, Thomas</au><au>Hofbeck, Michael</au><au>Singer, Helmut</au><au>Harms, Dieter</au><au>Deeg, Karl-Heinz</au><au>Benson, Lee</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determination of the anatomical size of ventricular septal defects on the basis of hemodynamic data and noninvasive assessment of pulmonary to systemic vascular resistance ratio rp/rs by doppler-echocardiography</atitle><jtitle>Catheterization and cardiovascular diagnosis</jtitle><addtitle>Cathet. 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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Biological and medical sciences
Cardiac Catheterization
Cardiology. Vascular system
congenital heart disease
Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
echocardiography
Echocardiography, Doppler
effective defect resistance
Female
Heart
Heart Septal Defects, Ventricular - diagnostic imaging
Heart Septal Defects, Ventricular - pathology
Hemodynamics - physiology
Humans
Infant
Male
Medical sciences
Models, Cardiovascular
Pulmonary Circulation - physiology
Regression Analysis
Vascular Resistance - physiology
ventricular septal defect
title Determination of the anatomical size of ventricular septal defects on the basis of hemodynamic data and noninvasive assessment of pulmonary to systemic vascular resistance ratio rp/rs by doppler-echocardiography
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