Regulatory properties of the pyruvate dehydrogenase complex from Escherichia coli. Studies on the thiamin diphosphate-dependent lag phase

The pyruvate dehydrogenase complex from Escherichia coli shows an appreciable lag phase (tau) of some minutes when its overall reaction rate was tested with very limiting amounts of thiamin diphosphate. tau depends on the concentration of thiamin diphosphate in a nonlinear fashion. Sodium diphosphat...

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Veröffentlicht in:	The Journal of biological chemistry 1983-06, Vol.258 (11), p.6912-6919
Hauptverfasser:	Horn, F, Bisswanger, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Diphosphates - pharmacology Escherichia coli - enzymology Kinetics Mathematics Protein Binding Pyruvate Dehydrogenase Complex - metabolism Thiamine Pyrophosphate - pharmacology
Online-Zugang:	Volltext
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