Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′) 2
Thirty-two immunoscintigraphic studies have been performed in 26 patients previously operated upon for rectosigmoid cancer, for an early detection of pelvic recurrence, employing 111In anti-CEA, F(ab′) 2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive val...
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Veröffentlicht in: | International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology Nuclear medicine and biology, 1991, Vol.18 (1), p.51-52 |
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container_title | International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology |
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creator | Aprile, C. Prati, U. Saponaro, R. Roveda, L. Carena, M. Gastaldo, L. |
description | Thirty-two immunoscintigraphic studies have been performed in 26 patients previously operated upon for rectosigmoid cancer, for an early detection of pelvic recurrence, employing
111In anti-CEA, F(ab′)
2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the
111In radioactivity used for RIS, improved diagnostic accuracy, ruling out the presence of tumors in 3 patients with false positive RIS. |
doi_str_mv | 10.1016/0883-2897(91)90046-N |
format | Article |
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111In anti-CEA, F(ab′)
2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the
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111In anti-CEA, F(ab′)
2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the
111In radioactivity used for RIS, improved diagnostic accuracy, ruling out the presence of tumors in 3 patients with false positive RIS.</description><subject>Antibodies, Monoclonal</subject><subject>Biological and medical sciences</subject><subject>Carcinoembryonic Antigen - immunology</subject><subject>Colorectal Neoplasms - diagnostic imaging</subject><subject>Colorectal Neoplasms - immunology</subject><subject>Humans</subject><subject>Indium Radioisotopes</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Neoplasm Recurrence, Local - diagnostic imaging</subject><subject>Neoplasm Recurrence, Local - immunology</subject><subject>Radionuclide Imaging</subject><issn>0883-2897</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFqFTEUhrNQaq2-gUIWIu1iNMlkMslGKJfWFkoF0XU4kzkpKTOTazJTaFc-k4_kk5jxXu6yqwP__53D4SPkHWefOOPqM9O6roQ27anhZ4YxqarbF-T4EL8ir3O-Z0xo2bRH5Egwzmqmjsn9d-hDDOO4THGIDobwBHOIE42ebnF4CI4mdEtKODnM1Kc4rsEcc7gbY-ipg1IkiuN2iI9huqOc8-uJwjSHanNxTi9Pofv7-88ZFW_ISw9Dxrf7eUJ-Xl782FxVN9--Xm_ObypXazlXHjqmJTqQyvRSCRCiBVSOc-1L4gFc07W1QqZM5w0a1Ey1ulOdhKYWpj4hH3d3tyn-WjDPdgzZ4TDAhHHJVjNpWN20BZQ70KWYc0JvtymMkB4tZ3bVald_dvVnDbf_tdrbsvZ-f3_pRuwPS3unpf-w7yEXoT4VQyEfMCmb2mhRsC87DIuLh4DJZhdWy31YBds-huf_-AcUPJcs</recordid><startdate>1991</startdate><enddate>1991</enddate><creator>Aprile, C.</creator><creator>Prati, U.</creator><creator>Saponaro, R.</creator><creator>Roveda, L.</creator><creator>Carena, M.</creator><creator>Gastaldo, L.</creator><general>Elsevier Ltd</general><general>Pergamon</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1991</creationdate><title>Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′) 2</title><author>Aprile, C. ; Prati, U. ; Saponaro, R. ; Roveda, L. ; Carena, M. ; Gastaldo, L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-fab084eca469d462a227ae6c118f69dfaac5b736e069bf9e9e80678b6b4a53293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Antibodies, Monoclonal</topic><topic>Biological and medical sciences</topic><topic>Carcinoembryonic Antigen - immunology</topic><topic>Colorectal Neoplasms - diagnostic imaging</topic><topic>Colorectal Neoplasms - immunology</topic><topic>Humans</topic><topic>Indium Radioisotopes</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Neoplasm Recurrence, Local - diagnostic imaging</topic><topic>Neoplasm Recurrence, Local - immunology</topic><topic>Radionuclide Imaging</topic><toplevel>online_resources</toplevel><creatorcontrib>Aprile, C.</creatorcontrib><creatorcontrib>Prati, U.</creatorcontrib><creatorcontrib>Saponaro, R.</creatorcontrib><creatorcontrib>Roveda, L.</creatorcontrib><creatorcontrib>Carena, M.</creatorcontrib><creatorcontrib>Gastaldo, L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aprile, C.</au><au>Prati, U.</au><au>Saponaro, R.</au><au>Roveda, L.</au><au>Carena, M.</au><au>Gastaldo, L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′) 2</atitle><jtitle>International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology</jtitle><addtitle>Int J Rad Appl Instrum B</addtitle><date>1991</date><risdate>1991</risdate><volume>18</volume><issue>1</issue><spage>51</spage><epage>52</epage><pages>51-52</pages><issn>0883-2897</issn><coden>NMBIEO</coden><abstract>Thirty-two immunoscintigraphic studies have been performed in 26 patients previously operated upon for rectosigmoid cancer, for an early detection of pelvic recurrence, employing
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2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the
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subjects | Antibodies, Monoclonal Biological and medical sciences Carcinoembryonic Antigen - immunology Colorectal Neoplasms - diagnostic imaging Colorectal Neoplasms - immunology Humans Indium Radioisotopes Investigative techniques, diagnostic techniques (general aspects) Medical sciences Neoplasm Recurrence, Local - diagnostic imaging Neoplasm Recurrence, Local - immunology Radionuclide Imaging |
title | Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′) 2 |
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