Inhibition by Low Molecular Weight Dextran of the Blood Pressure Fall and the Lowering of Plasminogen Proactivator Induced by Clinical Dextran in the Rat

: The intravenous injection into rats of dextran with a molecular weight of 1,000 (LMr dextran) in doses 200 mg/kg induced rapid, but transient falls in blood pressure. Pretreatment of the rats with LMr dextran 200 mg/kg caused a partial inhibition of the profound blood pressure fall induced by the...

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Veröffentlicht in:	Acta pharmacologica et toxicologica 1983-02, Vol.52 (2), p.143-149
Hauptverfasser:	Briseid, Gudrun, Briseid, Kjell
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals blood pressure Blood Pressure - drug effects Depression, Chemical Dextrans Dextrans - pharmacology Enzyme Precursors - metabolism kininogen Kininogens - pharmacology Male Molecular Weight plasminogen activator Plasminogen Activators - metabolism Prekallikrein - blood rat Rats Rats, Inbred Strains Time Factors
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