A Comparison of Surfactant as Immediate Prophylaxis and as Rescue Therapy in Newborns of Less Than 30 Weeks' Gestation

EXOGENOUS pulmonary surfactants have been administered into the trachea both to prevent and to treat the respiratory distress syndrome in premature infants. Randomized clinical trials of surfactant-replacement therapy 1 2 3 4 5 6 7 8 9 10 11 12 13 14 have demonstrated a reduction in the incidence an...

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Veröffentlicht in:	The New England journal of medicine 1991-03, Vol.324 (13), p.865-871
Hauptverfasser:	Kendig, James W, Notter, Robert H, Cox, Christopher, Reubens, Linda J, Davis, Jonathan M, Maniscalco, William M, Sinkin, Robert A, Bartoletti, Albert, Dweck, Harry S, Horgan, Michael J, Risemberg, Herman, Phelps, Dale L, Shapiro, Donald L
Format:	Artikel
Sprache:	eng
Schlagworte:	Babies Biological and medical sciences Clinical Protocols Clinical trials Colleges & universities Drug dosages Emergencies Gestational age Humans Infant, Newborn Infants Lungs Medical sciences Neonates Newborn babies Outcome and Process Assessment (Health Care) Oxygen Inhalation Therapy Patients Pediatrics Pharmacology. Drug treatments Pneumothorax Pneumothorax - etiology Pneumothorax - therapy Prophylaxis Proportional Hazards Models Pulmonary Surfactants - administration & dosage Pulmonary Surfactants - therapeutic use Respiration Respiratory distress syndrome Respiratory Distress Syndrome, Newborn - mortality Respiratory Distress Syndrome, Newborn - prevention & control Respiratory Distress Syndrome, Newborn - therapy Respiratory system Respiratory therapy Respiratory tract Resuscitation Surfactants Survival Trachea Ventilators
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