Primary cysts and tumors of the mediastinum
A retrospective analysis was performed on 230 patients with primary cysts and tumors of the mediastinum seen at our institution from January 1944 to April 1989. We divided these patients into two groups. Group 1 was seen before 1970 and group 2 was seen from January 1970 to April 1989. There was a s...
Gespeichert in:
| Veröffentlicht in: | The Annals of thoracic surgery 1991-03, Vol.51 (3), p.378-386 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 386 |
|---|---|
| container_issue | 3 |
| container_start_page | 378 |
| container_title | The Annals of thoracic surgery |
| container_volume | 51 |
| creator | Cohen, Amram J. Thompson, LeNardo Edwards, Fred H. Bellamy, Ronald F. |
| description | A retrospective analysis was performed on 230 patients with primary cysts and tumors of the mediastinum seen at our institution from January 1944 to April 1989. We divided these patients into two groups. Group 1 was seen before 1970 and group 2 was seen from January 1970 to April 1989. There was a significant increase in the prevalence of malignancy in group 2 (47.2% versus 17.1%;
p < 0.0001) due to an increase in the number of lymphomas (22.6% versus 3.5%;
p < 0.001) and malignant neurogenic tumors (6.8% versus 1.1%;
p = 0.0528). There was a significant increase in the number of malignant tumors in the anterior (59.5% versus 30.9%;
p = 0.0022) and paravertebral (28.5% versus 2.8%;
p = 0.0027) compartments in group 2. More patients with these tumors were symptomatic in group 2 (63.6% versus 5%;
p = 0.0422). There was an increase of ancillary diagnostic studies performed to evaluate these tumors (76.0% versus 34.5%;
p = 0.0422). Logistic regression analysis identified date of presentation (
p < 0.005), symptoms (
p < 0.01), size (
p < 0.005), and the anterior mediastinal compartment (
p < 0.005) as preoperative predictors of malignancy. The surgical approach to these tumors included more median sternotomy (30.1% versus 10.7%;
p = 0.0008), anterior mediastinotomy, and cervical mediastinoscopy in group 2 (1.1% versus 17.5%;
p = 0.0002). Long-term results support surgical resection in benign lesions and an aggressive multimodality approach to malignant lesions. |
| doi_str_mv | 10.1016/0003-4975(91)90848-K |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80459729</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>000349759190848K</els_id><sourcerecordid>80459729</sourcerecordid><originalsourceid>FETCH-LOGICAL-c534t-e65af9aacd2c0a38a0a787f62159f94d2d4deed2051aea1fece19550f528a0f43</originalsourceid><addsrcrecordid>eNp9kE1LAzEURYMotVb_gcJsFEVGk0wynWwEKX7Rgi50HZ7JC47MR01mhP57U6eoK1ch3PNu8g4hh4xeMMryS0pplgo1laeKnSlaiCKdb5Exk5KnOZdqm4x_kF2yF8J7vPIYj8iIKVUIJsbk_MmXNfhVYlahCwk0Nun6uvUhaV3SvWFSoy0hdGXT1_tkx0EV8GBzTsjL7c3z7D5dPN49zK4XqZGZ6FLMJTgFYCw3FLICKEyLqcvj08opYbkVFtFyKhkgMIcGmZKSOskj60Q2ISdD79K3Hz2GTtdlMFhV0GDbB11QIdWUqwiKATS-DcGj08thG82oXjvSawF6LUArpr8d6XkcO9r0969xvd-hQUrMjzc5BAOV89CYMvzBioyxWDwhVwOHUcZniV4HU2JjojGPptO2Lf__yBd4f4JV</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80459729</pqid></control><display><type>article</type><title>Primary cysts and tumors of the mediastinum</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Cohen, Amram J. ; Thompson, LeNardo ; Edwards, Fred H. ; Bellamy, Ronald F.</creator><creatorcontrib>Cohen, Amram J. ; Thompson, LeNardo ; Edwards, Fred H. ; Bellamy, Ronald F.</creatorcontrib><description><![CDATA[A retrospective analysis was performed on 230 patients with primary cysts and tumors of the mediastinum seen at our institution from January 1944 to April 1989. We divided these patients into two groups. Group 1 was seen before 1970 and group 2 was seen from January 1970 to April 1989. There was a significant increase in the prevalence of malignancy in group 2 (47.2% versus 17.1%;
p < 0.0001) due to an increase in the number of lymphomas (22.6% versus 3.5%;
p < 0.001) and malignant neurogenic tumors (6.8% versus 1.1%;
p = 0.0528). There was a significant increase in the number of malignant tumors in the anterior (59.5% versus 30.9%;
p = 0.0022) and paravertebral (28.5% versus 2.8%;
p = 0.0027) compartments in group 2. More patients with these tumors were symptomatic in group 2 (63.6% versus 5%;
p = 0.0422). There was an increase of ancillary diagnostic studies performed to evaluate these tumors (76.0% versus 34.5%;
p = 0.0422). Logistic regression analysis identified date of presentation (
p < 0.005), symptoms (
p < 0.01), size (
p < 0.005), and the anterior mediastinal compartment (
p < 0.005) as preoperative predictors of malignancy. The surgical approach to these tumors included more median sternotomy (30.1% versus 10.7%;
p = 0.0008), anterior mediastinotomy, and cervical mediastinoscopy in group 2 (1.1% versus 17.5%;
p = 0.0002). Long-term results support surgical resection in benign lesions and an aggressive multimodality approach to malignant lesions.]]></description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/0003-4975(91)90848-K</identifier><identifier>PMID: 1998414</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Humans ; Infant ; Infant, Newborn ; Male ; Mediastinal Cyst - diagnosis ; Mediastinal Cyst - mortality ; Mediastinal Cyst - pathology ; Mediastinal Cyst - surgery ; Medical sciences ; Middle Aged ; Pneumology ; Retrospective Studies ; Survival Rate ; Tumors of the respiratory system and mediastinum</subject><ispartof>The Annals of thoracic surgery, 1991-03, Vol.51 (3), p.378-386</ispartof><rights>1991 The Society of Thoracic Surgeons</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c534t-e65af9aacd2c0a38a0a787f62159f94d2d4deed2051aea1fece19550f528a0f43</citedby><cites>FETCH-LOGICAL-c534t-e65af9aacd2c0a38a0a787f62159f94d2d4deed2051aea1fece19550f528a0f43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,776,780,785,786,23910,23911,25119,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19831100$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1998414$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cohen, Amram J.</creatorcontrib><creatorcontrib>Thompson, LeNardo</creatorcontrib><creatorcontrib>Edwards, Fred H.</creatorcontrib><creatorcontrib>Bellamy, Ronald F.</creatorcontrib><title>Primary cysts and tumors of the mediastinum</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description><![CDATA[A retrospective analysis was performed on 230 patients with primary cysts and tumors of the mediastinum seen at our institution from January 1944 to April 1989. We divided these patients into two groups. Group 1 was seen before 1970 and group 2 was seen from January 1970 to April 1989. There was a significant increase in the prevalence of malignancy in group 2 (47.2% versus 17.1%;
p < 0.0001) due to an increase in the number of lymphomas (22.6% versus 3.5%;
p < 0.001) and malignant neurogenic tumors (6.8% versus 1.1%;
p = 0.0528). There was a significant increase in the number of malignant tumors in the anterior (59.5% versus 30.9%;
p = 0.0022) and paravertebral (28.5% versus 2.8%;
p = 0.0027) compartments in group 2. More patients with these tumors were symptomatic in group 2 (63.6% versus 5%;
p = 0.0422). There was an increase of ancillary diagnostic studies performed to evaluate these tumors (76.0% versus 34.5%;
p = 0.0422). Logistic regression analysis identified date of presentation (
p < 0.005), symptoms (
p < 0.01), size (
p < 0.005), and the anterior mediastinal compartment (
p < 0.005) as preoperative predictors of malignancy. The surgical approach to these tumors included more median sternotomy (30.1% versus 10.7%;
p = 0.0008), anterior mediastinotomy, and cervical mediastinoscopy in group 2 (1.1% versus 17.5%;
p = 0.0002). Long-term results support surgical resection in benign lesions and an aggressive multimodality approach to malignant lesions.]]></description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Mediastinal Cyst - diagnosis</subject><subject>Mediastinal Cyst - mortality</subject><subject>Mediastinal Cyst - pathology</subject><subject>Mediastinal Cyst - surgery</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pneumology</subject><subject>Retrospective Studies</subject><subject>Survival Rate</subject><subject>Tumors of the respiratory system and mediastinum</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEURYMotVb_gcJsFEVGk0wynWwEKX7Rgi50HZ7JC47MR01mhP57U6eoK1ch3PNu8g4hh4xeMMryS0pplgo1laeKnSlaiCKdb5Exk5KnOZdqm4x_kF2yF8J7vPIYj8iIKVUIJsbk_MmXNfhVYlahCwk0Nun6uvUhaV3SvWFSoy0hdGXT1_tkx0EV8GBzTsjL7c3z7D5dPN49zK4XqZGZ6FLMJTgFYCw3FLICKEyLqcvj08opYbkVFtFyKhkgMIcGmZKSOskj60Q2ISdD79K3Hz2GTtdlMFhV0GDbB11QIdWUqwiKATS-DcGj08thG82oXjvSawF6LUArpr8d6XkcO9r0969xvd-hQUrMjzc5BAOV89CYMvzBioyxWDwhVwOHUcZniV4HU2JjojGPptO2Lf__yBd4f4JV</recordid><startdate>19910301</startdate><enddate>19910301</enddate><creator>Cohen, Amram J.</creator><creator>Thompson, LeNardo</creator><creator>Edwards, Fred H.</creator><creator>Bellamy, Ronald F.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19910301</creationdate><title>Primary cysts and tumors of the mediastinum</title><author>Cohen, Amram J. ; Thompson, LeNardo ; Edwards, Fred H. ; Bellamy, Ronald F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c534t-e65af9aacd2c0a38a0a787f62159f94d2d4deed2051aea1fece19550f528a0f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Mediastinal Cyst - diagnosis</topic><topic>Mediastinal Cyst - mortality</topic><topic>Mediastinal Cyst - pathology</topic><topic>Mediastinal Cyst - surgery</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pneumology</topic><topic>Retrospective Studies</topic><topic>Survival Rate</topic><topic>Tumors of the respiratory system and mediastinum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cohen, Amram J.</creatorcontrib><creatorcontrib>Thompson, LeNardo</creatorcontrib><creatorcontrib>Edwards, Fred H.</creatorcontrib><creatorcontrib>Bellamy, Ronald F.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cohen, Amram J.</au><au>Thompson, LeNardo</au><au>Edwards, Fred H.</au><au>Bellamy, Ronald F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary cysts and tumors of the mediastinum</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1991-03-01</date><risdate>1991</risdate><volume>51</volume><issue>3</issue><spage>378</spage><epage>386</epage><pages>378-386</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract><![CDATA[A retrospective analysis was performed on 230 patients with primary cysts and tumors of the mediastinum seen at our institution from January 1944 to April 1989. We divided these patients into two groups. Group 1 was seen before 1970 and group 2 was seen from January 1970 to April 1989. There was a significant increase in the prevalence of malignancy in group 2 (47.2% versus 17.1%;
p < 0.0001) due to an increase in the number of lymphomas (22.6% versus 3.5%;
p < 0.001) and malignant neurogenic tumors (6.8% versus 1.1%;
p = 0.0528). There was a significant increase in the number of malignant tumors in the anterior (59.5% versus 30.9%;
p = 0.0022) and paravertebral (28.5% versus 2.8%;
p = 0.0027) compartments in group 2. More patients with these tumors were symptomatic in group 2 (63.6% versus 5%;
p = 0.0422). There was an increase of ancillary diagnostic studies performed to evaluate these tumors (76.0% versus 34.5%;
p = 0.0422). Logistic regression analysis identified date of presentation (
p < 0.005), symptoms (
p < 0.01), size (
p < 0.005), and the anterior mediastinal compartment (
p < 0.005) as preoperative predictors of malignancy. The surgical approach to these tumors included more median sternotomy (30.1% versus 10.7%;
p = 0.0008), anterior mediastinotomy, and cervical mediastinoscopy in group 2 (1.1% versus 17.5%;
p = 0.0002). Long-term results support surgical resection in benign lesions and an aggressive multimodality approach to malignant lesions.]]></abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>1998414</pmid><doi>10.1016/0003-4975(91)90848-K</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-4975 |
| ispartof | The Annals of thoracic surgery, 1991-03, Vol.51 (3), p.378-386 |
| issn | 0003-4975 1552-6259 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80459729 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Biological and medical sciences Child Child, Preschool Female Follow-Up Studies Humans Infant Infant, Newborn Male Mediastinal Cyst - diagnosis Mediastinal Cyst - mortality Mediastinal Cyst - pathology Mediastinal Cyst - surgery Medical sciences Middle Aged Pneumology Retrospective Studies Survival Rate Tumors of the respiratory system and mediastinum |
| title | Primary cysts and tumors of the mediastinum |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T04%3A50%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Primary%20cysts%20and%20tumors%20of%20the%20mediastinum&rft.jtitle=The%20Annals%20of%20thoracic%20surgery&rft.au=Cohen,%20Amram%20J.&rft.date=1991-03-01&rft.volume=51&rft.issue=3&rft.spage=378&rft.epage=386&rft.pages=378-386&rft.issn=0003-4975&rft.eissn=1552-6259&rft.coden=ATHSAK&rft_id=info:doi/10.1016/0003-4975(91)90848-K&rft_dat=%3Cproquest_cross%3E80459729%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80459729&rft_id=info:pmid/1998414&rft_els_id=000349759190848K&rfr_iscdi=true |