Application of the Microcapsule Agglutination Test to Serologic Studies of an Early Stage of Lyme Disease in Japan
We previously found that the microcapsule agglutination test (MCAT) is valuable and convenient for the diagnosis of leptospirosis. We describe the application of MCAT to the early diagnosis of Lyme disease. The present studies clearly indicated that MCAT is more sensitive than ELISA for detecting sp...
Gespeichert in:
| Veröffentlicht in: | The Journal of infectious diseases 1991-03, Vol.163 (3), p.682-683 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 683 |
|---|---|
| container_issue | 3 |
| container_start_page | 682 |
| container_title | The Journal of infectious diseases |
| container_volume | 163 |
| creator | Arimitsu, Yoshiko Takashima, Iwao Yoshii, Zensaku Higashi, Yoshifumi Kameyama, Shoichi Mizuguchi, Junichiro |
| description | We previously found that the microcapsule agglutination test (MCAT) is valuable and convenient for the diagnosis of leptospirosis. We describe the application of MCAT to the early diagnosis of Lyme disease. The present studies clearly indicated that MCAT is more sensitive than ELISA for detecting specific antibodies from early Lyme disease patients. One reason MCAT is superior to conventional ELISA is that it may detect lower-avidity antibody, the main isotype in early immune response. MCAT would be especially valuable in the small laboratory because of its ease of use and lower cost. |
| doi_str_mv | 10.1093/infdis/163.3.682 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_80452507</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>30123197</jstor_id><sourcerecordid>30123197</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3422-7c1bef6e9dea472fdbdad36546cff8c6876e364bf468a8558fd77e1c9070233f3</originalsourceid><addsrcrecordid>eNqFkc1rGzEQxUVpSR03914KOvW2jrRafR1NmsZJnfbglIRehKwduUrXq620C_F_3zUbkmNBIJj33vCYH0IfKVlQotl5aH0d8jkVbMEWQpVv0IxyJgshKHuLZoSUZUGV1u_Rac6PhJCKCXmCTqjWXFZ6htKy65rgbB9ii6PH_W_At8Gl6GyXhwbwcrdrhj60k-MOco_7iDeQYhN3weFNP9QB8jFrW3xpU3MYZ3YHx8n6sAf8JWSwGXBo8Y3tbPsBvfO2yXD2_M_Rz6-XdxerYv3j6vpiuS4cq8ba0tEteAG6BlvJ0tfb2tZM8Eo475UTSgpgotr6SiirOFe-lhKo00SSkjHP5ujztLdL8e8wFjf7kB00jW0hDtkoUvGSE_lfI-Vaaja-OSKTcbxPzgm86VLY23QwlJgjDzPxMCMPw8zIY4x8et49bPdQvwYmAK_6Y-5jepEZoSWj-titmPSQe3h60W36Y4RkkpvVwy_z7V7drh42V-Y7-wfLkKGH</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15979379</pqid></control><display><type>article</type><title>Application of the Microcapsule Agglutination Test to Serologic Studies of an Early Stage of Lyme Disease in Japan</title><source>MEDLINE</source><source>Jstor Complete Legacy</source><creator>Arimitsu, Yoshiko ; Takashima, Iwao ; Yoshii, Zensaku ; Higashi, Yoshifumi ; Kameyama, Shoichi ; Mizuguchi, Junichiro</creator><creatorcontrib>Arimitsu, Yoshiko ; Takashima, Iwao ; Yoshii, Zensaku ; Higashi, Yoshifumi ; Kameyama, Shoichi ; Mizuguchi, Junichiro</creatorcontrib><description>We previously found that the microcapsule agglutination test (MCAT) is valuable and convenient for the diagnosis of leptospirosis. We describe the application of MCAT to the early diagnosis of Lyme disease. The present studies clearly indicated that MCAT is more sensitive than ELISA for detecting specific antibodies from early Lyme disease patients. One reason MCAT is superior to conventional ELISA is that it may detect lower-avidity antibody, the main isotype in early immune response. MCAT would be especially valuable in the small laboratory because of its ease of use and lower cost.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/163.3.682</identifier><identifier>PMID: 1995749</identifier><language>eng</language><publisher>United States: University Chicago Press</publisher><subject>Agglutination Tests ; Antibodies ; Antigens ; Capsules ; Correspondence ; Enzyme linked immunosorbent assay ; Humans ; Japan ; Leptospirosis ; Lyme disease ; Lyme Disease - diagnosis ; Nervous system diseases ; Sensitivity and Specificity ; Standardized tests ; Washing</subject><ispartof>The Journal of infectious diseases, 1991-03, Vol.163 (3), p.682-683</ispartof><rights>Copyright 1990 University of Chicago</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3422-7c1bef6e9dea472fdbdad36546cff8c6876e364bf468a8558fd77e1c9070233f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/30123197$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/30123197$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,777,781,800,27905,27906,57998,58231</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1995749$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arimitsu, Yoshiko</creatorcontrib><creatorcontrib>Takashima, Iwao</creatorcontrib><creatorcontrib>Yoshii, Zensaku</creatorcontrib><creatorcontrib>Higashi, Yoshifumi</creatorcontrib><creatorcontrib>Kameyama, Shoichi</creatorcontrib><creatorcontrib>Mizuguchi, Junichiro</creatorcontrib><title>Application of the Microcapsule Agglutination Test to Serologic Studies of an Early Stage of Lyme Disease in Japan</title><title>The Journal of infectious diseases</title><addtitle>J Infect Dis</addtitle><description>We previously found that the microcapsule agglutination test (MCAT) is valuable and convenient for the diagnosis of leptospirosis. We describe the application of MCAT to the early diagnosis of Lyme disease. The present studies clearly indicated that MCAT is more sensitive than ELISA for detecting specific antibodies from early Lyme disease patients. One reason MCAT is superior to conventional ELISA is that it may detect lower-avidity antibody, the main isotype in early immune response. MCAT would be especially valuable in the small laboratory because of its ease of use and lower cost.</description><subject>Agglutination Tests</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Capsules</subject><subject>Correspondence</subject><subject>Enzyme linked immunosorbent assay</subject><subject>Humans</subject><subject>Japan</subject><subject>Leptospirosis</subject><subject>Lyme disease</subject><subject>Lyme Disease - diagnosis</subject><subject>Nervous system diseases</subject><subject>Sensitivity and Specificity</subject><subject>Standardized tests</subject><subject>Washing</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1rGzEQxUVpSR03914KOvW2jrRafR1NmsZJnfbglIRehKwduUrXq620C_F_3zUbkmNBIJj33vCYH0IfKVlQotl5aH0d8jkVbMEWQpVv0IxyJgshKHuLZoSUZUGV1u_Rac6PhJCKCXmCTqjWXFZ6htKy65rgbB9ii6PH_W_At8Gl6GyXhwbwcrdrhj60k-MOco_7iDeQYhN3weFNP9QB8jFrW3xpU3MYZ3YHx8n6sAf8JWSwGXBo8Y3tbPsBvfO2yXD2_M_Rz6-XdxerYv3j6vpiuS4cq8ba0tEteAG6BlvJ0tfb2tZM8Eo475UTSgpgotr6SiirOFe-lhKo00SSkjHP5ujztLdL8e8wFjf7kB00jW0hDtkoUvGSE_lfI-Vaaja-OSKTcbxPzgm86VLY23QwlJgjDzPxMCMPw8zIY4x8et49bPdQvwYmAK_6Y-5jepEZoSWj-titmPSQe3h60W36Y4RkkpvVwy_z7V7drh42V-Y7-wfLkKGH</recordid><startdate>199103</startdate><enddate>199103</enddate><creator>Arimitsu, Yoshiko</creator><creator>Takashima, Iwao</creator><creator>Yoshii, Zensaku</creator><creator>Higashi, Yoshifumi</creator><creator>Kameyama, Shoichi</creator><creator>Mizuguchi, Junichiro</creator><general>University Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T5</scope><scope>C1K</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>199103</creationdate><title>Application of the Microcapsule Agglutination Test to Serologic Studies of an Early Stage of Lyme Disease in Japan</title><author>Arimitsu, Yoshiko ; Takashima, Iwao ; Yoshii, Zensaku ; Higashi, Yoshifumi ; Kameyama, Shoichi ; Mizuguchi, Junichiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3422-7c1bef6e9dea472fdbdad36546cff8c6876e364bf468a8558fd77e1c9070233f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Agglutination Tests</topic><topic>Antibodies</topic><topic>Antigens</topic><topic>Capsules</topic><topic>Correspondence</topic><topic>Enzyme linked immunosorbent assay</topic><topic>Humans</topic><topic>Japan</topic><topic>Leptospirosis</topic><topic>Lyme disease</topic><topic>Lyme Disease - diagnosis</topic><topic>Nervous system diseases</topic><topic>Sensitivity and Specificity</topic><topic>Standardized tests</topic><topic>Washing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arimitsu, Yoshiko</creatorcontrib><creatorcontrib>Takashima, Iwao</creatorcontrib><creatorcontrib>Yoshii, Zensaku</creatorcontrib><creatorcontrib>Higashi, Yoshifumi</creatorcontrib><creatorcontrib>Kameyama, Shoichi</creatorcontrib><creatorcontrib>Mizuguchi, Junichiro</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Immunology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arimitsu, Yoshiko</au><au>Takashima, Iwao</au><au>Yoshii, Zensaku</au><au>Higashi, Yoshifumi</au><au>Kameyama, Shoichi</au><au>Mizuguchi, Junichiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Application of the Microcapsule Agglutination Test to Serologic Studies of an Early Stage of Lyme Disease in Japan</atitle><jtitle>The Journal of infectious diseases</jtitle><addtitle>J Infect Dis</addtitle><date>1991-03</date><risdate>1991</risdate><volume>163</volume><issue>3</issue><spage>682</spage><epage>683</epage><pages>682-683</pages><issn>0022-1899</issn><eissn>1537-6613</eissn><abstract>We previously found that the microcapsule agglutination test (MCAT) is valuable and convenient for the diagnosis of leptospirosis. We describe the application of MCAT to the early diagnosis of Lyme disease. The present studies clearly indicated that MCAT is more sensitive than ELISA for detecting specific antibodies from early Lyme disease patients. One reason MCAT is superior to conventional ELISA is that it may detect lower-avidity antibody, the main isotype in early immune response. MCAT would be especially valuable in the small laboratory because of its ease of use and lower cost.</abstract><cop>United States</cop><pub>University Chicago Press</pub><pmid>1995749</pmid><doi>10.1093/infdis/163.3.682</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1899 |
| ispartof | The Journal of infectious diseases, 1991-03, Vol.163 (3), p.682-683 |
| issn | 0022-1899 1537-6613 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80452507 |
| source | MEDLINE; Jstor Complete Legacy |
| subjects | Agglutination Tests Antibodies Antigens Capsules Correspondence Enzyme linked immunosorbent assay Humans Japan Leptospirosis Lyme disease Lyme Disease - diagnosis Nervous system diseases Sensitivity and Specificity Standardized tests Washing |
| title | Application of the Microcapsule Agglutination Test to Serologic Studies of an Early Stage of Lyme Disease in Japan |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T03%3A58%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Application%20of%20the%20Microcapsule%20Agglutination%20Test%20to%20Serologic%20Studies%20of%20an%20Early%20Stage%20of%20Lyme%20Disease%20in%20Japan&rft.jtitle=The%20Journal%20of%20infectious%20diseases&rft.au=Arimitsu,%20Yoshiko&rft.date=1991-03&rft.volume=163&rft.issue=3&rft.spage=682&rft.epage=683&rft.pages=682-683&rft.issn=0022-1899&rft.eissn=1537-6613&rft_id=info:doi/10.1093/infdis/163.3.682&rft_dat=%3Cjstor_proqu%3E30123197%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15979379&rft_id=info:pmid/1995749&rft_jstor_id=30123197&rfr_iscdi=true |