Role of 5'-deoxy-5'-methylthioadenosine in growth of several microbial B12 requirers

5'-Deoxy-5'-Methylthioadenosine (MTA) figures in cellular methionine and polyamine syntheses. It replaces B12 for growth of the chrysomonad protozoan Poteriochromonas malhamensis at a ratio of MTA:B12 of approximatly 10,000,000:1 (by weight). MTA does not replace B12 for other B12-requirer...

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Veröffentlicht in:	Life sciences (1973) 1991, Vol.48 (2), p.163-173
Hauptverfasser:	BAKER, H, FRANK, O, BAKER, E. R, HUTNER, S. H, DEANGELIS, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - metabolism Analytical, structural and metabolic biochemistry Animals Bacteria - metabolism Biological and medical sciences Cell Division - physiology Deoxyadenosines Escherichia coli - metabolism Euglena gracilis - metabolism Eukaryota - metabolism Fundamental and applied biological sciences. Psychology Lactobacillus - metabolism Nucleic acids Nucleic bases, nucleotides Thionucleosides - metabolism Vitamin B 12 - metabolism
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