Diminution of parotid IgA secretion in an elderly black population taking antihypertension medications

A study was conducted with two randomly selected groups of black patients. Group A, the control group, consisted of 15 elderly healthy normotensive patients, whereas group B consisted of 19 patients with hypertension who were taking antihypertension medications. Parotid salivary samples were collect...

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Veröffentlicht in:Oral surgery, oral medicine, oral pathology oral medicine, oral pathology, 1991, Vol.71 (1), p.50-54
Hauptverfasser: Streckfus, Charles F., Welsh, Sharon, Strahl, Robert C.
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creator Streckfus, Charles F.
Welsh, Sharon
Strahl, Robert C.
description A study was conducted with two randomly selected groups of black patients. Group A, the control group, consisted of 15 elderly healthy normotensive patients, whereas group B consisted of 19 patients with hypertension who were taking antihypertension medications. Parotid salivary samples were collected from each patient with the Lashley cup and were analyzed for IgA, total protein, and electrolytes. The results showed a diminution of sodium ( p < 0.01), salivary flow ( p < 0.23), and IgA secretion ( p < 0.022) in the medicated group. The medicated group showed an increase in the incidence of root decay, which was significant at the p < 0.035 level.
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Group A, the control group, consisted of 15 elderly healthy normotensive patients, whereas group B consisted of 19 patients with hypertension who were taking antihypertension medications. Parotid salivary samples were collected from each patient with the Lashley cup and were analyzed for IgA, total protein, and electrolytes. The results showed a diminution of sodium ( p &lt; 0.01), salivary flow ( p &lt; 0.23), and IgA secretion ( p &lt; 0.022) in the medicated group. 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Group A, the control group, consisted of 15 elderly healthy normotensive patients, whereas group B consisted of 19 patients with hypertension who were taking antihypertension medications. Parotid salivary samples were collected from each patient with the Lashley cup and were analyzed for IgA, total protein, and electrolytes. The results showed a diminution of sodium ( p &lt; 0.01), salivary flow ( p &lt; 0.23), and IgA secretion ( p &lt; 0.022) in the medicated group. 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subjects Adrenergic beta-Antagonists - adverse effects
African Continental Ancestry Group
Aged
Antihypertensive agents
Benzothiadiazines
Biological and medical sciences
Cardiovascular system
Dentistry
Diuretics
Electrolytes - analysis
Female
Humans
Hypertension - drug therapy
Immunoglobulin A, Secretory - analysis
Male
Medical sciences
Parotid Gland - drug effects
Pharmacology. Drug treatments
Regression Analysis
Saliva - chemistry
Salivary Proteins and Peptides - analysis
Sodium Chloride Symporter Inhibitors - adverse effects
title Diminution of parotid IgA secretion in an elderly black population taking antihypertension medications
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