Donor-specific cytotoxic T lymphocyte hyporesponsiveness following renal transplantation in patients pretreated with donor-specific transfusions

Our purpose was to investigate the mechanism of the continuing beneficial effect of donor-specific transfusions in the cyclosporine era. We describe the development of donor-specific cytotoxic T lymphocyte hyporesponsiveness in peripheral blood lymphocytes obtained up to 2 years posttransplant in pa...

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Veröffentlicht in:	Transplantation 1991-02, Vol.51 (2), p.320-324
Hauptverfasser:	GRAILER, A. P, SOLLINGER, H. W, KAWAMURA, T, BURLINGHAM, W. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Transfusion Cytotoxicity, Immunologic Histocompatibility Humans Interleukin-2 - pharmacology Kidney Transplantation - immunology Kidney Transplantation - methods Medical sciences Recombinant Proteins Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Helper-Inducer - immunology Time Factors Tissue Donors
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