Aging-related decreases in hepatic mitochondrial and cytosolic δ-aminolevulinic acid synthase during experimental porphyria

The basal- and allylisopropylacetamide-induced activities of the first enzyme of heme biosynthesis, δ-aminolevulinic acid synthase (ALAS) were measured in hepatic mitochondria and cytosol of young, adult, and aged Fisher 344 rats. The total cellular ALAS activity induced by allylisopropylacetamide d...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1983-04, Vol.222 (1), p.150-157
Hauptverfasser:	Scotto, Anthony W., Rinehart, Ronald W., Beattie, Diana S.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Aminolevulinate Synthetase - isolation & purification Aging Allylisopropylacetamide - pharmacology Animals Cytosol - enzymology Disease Models, Animal Male Mitochondria, Liver - enzymology Porphyrias - enzymology Rats Rats, Inbred F344
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