Heterogeneity of the glucocorticoid receptors: Molecular transformations during activation, detected by electrofocusing

Isoelectric focusing (IEF) of glucocorticoid receptor (GR) of the neural retina of the 14-day chick embryo was conducted under conditions that yielded quantitative recovery of binding activity. IEF of the cytosol, equilibrated with [ 3H]triamcinolone acetonide (TA) at 0–2 °C yielded three major TA-G...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1983-03, Vol.221 (2), p.343-353
Hauptverfasser:	Ben-Or, Sarah, Chrambach, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Nucleus - metabolism Chemical Phenomena Chemistry Chick Embryo Cytosol - metabolism Isoelectric Focusing Protein Conformation Receptors, Glucocorticoid - isolation & purification Receptors, Steroid - isolation & purification Retina - metabolism Temperature
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