Effects of Local Reduction in Pressure on Distensibility and Composition of Cerebral Arterioles

This study examined effects of local reductions in mean and pulse pressures on cerebral arterioles in normotensive Wistar-Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP). WKY and SHRSP underwent clipping of one carotid artery at 1 month of age. At 10–12 months of age, mecha...

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Veröffentlicht in:	Circulation research 1991-02, Vol.68 (2), p.338-351
Hauptverfasser:	Baumbach, Gary L, Siems, Jay E, Heistad, Donald D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterial hypertension. Arterial hypotension Arterioles - metabolism Arterioles - pathology Arterioles - physiology Biological and medical sciences Blood and lymphatic vessels Blood Pressure Cardiology. Vascular system Cerebrovascular Circulation Cerebrovascular Disorders - etiology Collagen - metabolism Disease Susceptibility Elastin - metabolism Experimental diseases Hypertrophy Medical sciences Muscle, Smooth - metabolism Muscle, Smooth - ultrastructure Pia Mater - blood supply Rats Rats, Inbred SHR Rats, Inbred WKY
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