The CSF and plasma pharmacokinetics of sufentanil after intrathecal administration

Eight patients (7 men and 1 woman, 45-68 yr old) scheduled to undergo thoracotomy were given, preoperatively, 15 micrograms sufentanil in the lumbar intrathecal space for a study of cerebrospinal fluid (CSF) and plasma kinetics of sufentanil. Multiple samples of plasma and CSF from the lumbar region...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 1991-02, Vol.74 (2), p.264-269
Hauptverfasser:	HANSDOTTIR, V, HEDNER, T, WOESTENBORGHS, R, NORDBERG, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analgesics Analgesics, Opioid - blood Analgesics, Opioid - cerebrospinal fluid Analgesics, Opioid - pharmacokinetics Biological and medical sciences Fentanyl - analogs & derivatives Fentanyl - blood Fentanyl - cerebrospinal fluid Fentanyl - pharmacokinetics Humans Infant Injections, Spinal Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Sufentanil
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