Suppression of shock elicited target biting by analgesic midbrain stimulation
Rats with chronic electrodes in or near the central gray (PVG) of the midbrain were tested with a tail pinch to determine analgesic brain stimulation parameters. Then blocks of tail shock, adjusted to a level that produced consistent biting on an inanimate target, were alternated with blocks of tail...
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| Veröffentlicht in: | Physiology & behavior 1983, Vol.30 (1), p.169-172 |
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| container_title | Physiology & behavior |
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| creator | Renfrew, J.W. Leroy, J.A. |
| description | Rats with chronic electrodes in or near the central gray (PVG) of the midbrain were tested with a tail pinch to determine analgesic brain stimulation parameters. Then blocks of tail shock, adjusted to a level that produced consistent biting on an inanimate target, were alternated with blocks of tail shock preceded by PVG stimulation. Biting following the tail shock was reduced or eliminated when the brain stimulation preceded the shock. It was concluded that stimulation in the PVG region reduces target biting produced by nociceptive stimulation, probably via an analgesic effect. Also, no biting was associated with brain stimulation, indicating that the bite suppression function is separate from the attack producing function of other central gray areas. |
| doi_str_mv | 10.1016/0031-9384(83)90055-0 |
| format | Article |
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Then blocks of tail shock, adjusted to a level that produced consistent biting on an inanimate target, were alternated with blocks of tail shock preceded by PVG stimulation. Biting following the tail shock was reduced or eliminated when the brain stimulation preceded the shock. It was concluded that stimulation in the PVG region reduces target biting produced by nociceptive stimulation, probably via an analgesic effect. Also, no biting was associated with brain stimulation, indicating that the bite suppression function is separate from the attack producing function of other central gray areas.</description><identifier>ISSN: 0031-9384</identifier><identifier>EISSN: 1873-507X</identifier><identifier>DOI: 10.1016/0031-9384(83)90055-0</identifier><identifier>PMID: 6682236</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aggression ; Aggression - physiology ; Animals ; Brain stimulation analgesia ; Electric Stimulation ; Electroshock ; Humans ; Male ; Midbrain central gray ; Muridae ; Neural Inhibition ; Nociceptors - physiology ; Periaqueductal Gray - physiology ; Rat ; Tail shock ; Target biting</subject><ispartof>Physiology & behavior, 1983, Vol.30 (1), p.169-172</ispartof><rights>1983</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-e3463867bea38fad62053ce7cf6396adca668e5977b5c2fad4cc06d1e6564ead3</citedby><cites>FETCH-LOGICAL-c388t-e3463867bea38fad62053ce7cf6396adca668e5977b5c2fad4cc06d1e6564ead3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0031938483900550$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6682236$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Renfrew, J.W.</creatorcontrib><creatorcontrib>Leroy, J.A.</creatorcontrib><title>Suppression of shock elicited target biting by analgesic midbrain stimulation</title><title>Physiology & behavior</title><addtitle>Physiol Behav</addtitle><description>Rats with chronic electrodes in or near the central gray (PVG) of the midbrain were tested with a tail pinch to determine analgesic brain stimulation parameters. 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Also, no biting was associated with brain stimulation, indicating that the bite suppression function is separate from the attack producing function of other central gray areas.</description><subject>Aggression</subject><subject>Aggression - physiology</subject><subject>Animals</subject><subject>Brain stimulation analgesia</subject><subject>Electric Stimulation</subject><subject>Electroshock</subject><subject>Humans</subject><subject>Male</subject><subject>Midbrain central gray</subject><subject>Muridae</subject><subject>Neural Inhibition</subject><subject>Nociceptors - physiology</subject><subject>Periaqueductal Gray - physiology</subject><subject>Rat</subject><subject>Tail shock</subject><subject>Target biting</subject><issn>0031-9384</issn><issn>1873-507X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LxDAQhoMo6_rxDxRyEj1Uk06bphdBxC9QPKjgLaTJdI32Y01SYf-9XXfxqHOZwzzzzvAQcsDZKWdcnDEGPClBZscSTkrG8jxhG2TKZQFJzorXTTL9RbbJTgjvbCzIYEImQsg0BTElD0_DfO4xBNd3tK9peOvNB8XGGRfR0qj9DCOtXHTdjFYLqjvdzDA4Q1tnK69dR0N07dDoOCbska1aNwH3132XvFxfPV_eJvePN3eXF_eJASljgpAJkKKoUIOstRUpy8FgYWoBpdDW6PE_zMuiqHKTjkBmDBOWo8hFhtrCLjla5c59_zlgiKp1wWDT6A77ISjJslSmWfEvyCEXJZR8BLMVaHwfgsdazb1rtV8oztRSt1q6VEuXSoL60a3YuHa4zh-qFu3v0trvOD9fzXG08eXQq2Acdgat82iisr37-8A3qBKPzA</recordid><startdate>1983</startdate><enddate>1983</enddate><creator>Renfrew, J.W.</creator><creator>Leroy, J.A.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>1983</creationdate><title>Suppression of shock elicited target biting by analgesic midbrain stimulation</title><author>Renfrew, J.W. ; Leroy, J.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-e3463867bea38fad62053ce7cf6396adca668e5977b5c2fad4cc06d1e6564ead3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Aggression</topic><topic>Aggression - physiology</topic><topic>Animals</topic><topic>Brain stimulation analgesia</topic><topic>Electric Stimulation</topic><topic>Electroshock</topic><topic>Humans</topic><topic>Male</topic><topic>Midbrain central gray</topic><topic>Muridae</topic><topic>Neural Inhibition</topic><topic>Nociceptors - physiology</topic><topic>Periaqueductal Gray - physiology</topic><topic>Rat</topic><topic>Tail shock</topic><topic>Target biting</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Renfrew, J.W.</creatorcontrib><creatorcontrib>Leroy, J.A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Physiology & behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Renfrew, J.W.</au><au>Leroy, J.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Suppression of shock elicited target biting by analgesic midbrain stimulation</atitle><jtitle>Physiology & behavior</jtitle><addtitle>Physiol Behav</addtitle><date>1983</date><risdate>1983</risdate><volume>30</volume><issue>1</issue><spage>169</spage><epage>172</epage><pages>169-172</pages><issn>0031-9384</issn><eissn>1873-507X</eissn><abstract>Rats with chronic electrodes in or near the central gray (PVG) of the midbrain were tested with a tail pinch to determine analgesic brain stimulation parameters. Then blocks of tail shock, adjusted to a level that produced consistent biting on an inanimate target, were alternated with blocks of tail shock preceded by PVG stimulation. Biting following the tail shock was reduced or eliminated when the brain stimulation preceded the shock. It was concluded that stimulation in the PVG region reduces target biting produced by nociceptive stimulation, probably via an analgesic effect. Also, no biting was associated with brain stimulation, indicating that the bite suppression function is separate from the attack producing function of other central gray areas.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>6682236</pmid><doi>10.1016/0031-9384(83)90055-0</doi><tpages>4</tpages></addata></record> |
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| ispartof | Physiology & behavior, 1983, Vol.30 (1), p.169-172 |
| issn | 0031-9384 1873-507X |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aggression Aggression - physiology Animals Brain stimulation analgesia Electric Stimulation Electroshock Humans Male Midbrain central gray Muridae Neural Inhibition Nociceptors - physiology Periaqueductal Gray - physiology Rat Tail shock Target biting |
| title | Suppression of shock elicited target biting by analgesic midbrain stimulation |
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