Hyperphosphorylation of CD20 in hairy cells. Alteration by low molecular weight B cell growth factor and IFN-alpha

Hairy cell leukemia (HCL) is a B cell tumor affecting the pre-plasma stage of B cell differentiation. Hairy cells produce B cell growth factor (BCGF)-related growth factor(s) and we have previously shown that low mol wt (LMW)-BCGF-induced proliferation of hairy cells is inhibited in vitro and in viv...

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Veröffentlicht in:	The Journal of immunology (1950) 1991-02, Vol.146 (3), p.870-878
Hauptverfasser:	Genot, E, Valentine, MA, Degos, L, Sigaux, F, Kolb, JP
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - metabolism Antigens, CD20 Antigens, Differentiation, B-Lymphocyte - metabolism Cell Division - drug effects Humans Interferon Type I - pharmacology Interleukin-4 - pharmacology Leukemia, Hairy Cell - immunology Leukemia, Hairy Cell - therapy Molecular Weight Phosphorylation Tumor Cells, Cultured
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