Kinetics of TNF, IL-6, and IL-8 gene expression in LPS-stimulated human whole blood

While the production of tumor necrosis factor (TNF) and interleukin-6 (IL-6) in septic shock and other inflammatory states is well established, the role of interleukin-8 (IL-8), a recently described neutrophil chemoattractant and activator, has yet to be fully elucidated. Using lipopolysaccharide (L...

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Veröffentlicht in:	Biochemical and biophysical research communications 1991-01, Vol.174 (1), p.18-24
Hauptverfasser:	DeForge, L.E., Remick, D.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation Humans Interleukin-6 - biosynthesis Interleukin-6 - genetics Interleukin-8 - biosynthesis Interleukin-8 - genetics Kinetics Leukocytes - metabolism Lipopolysaccharides - pharmacology Male Molecular and cellular biology Molecular genetics Molecular Sequence Data RNA, Messenger - metabolism Transcriptional Activation Tumor Necrosis Factor-alpha - biosynthesis Tumor Necrosis Factor-alpha - genetics
Online-Zugang:	Volltext
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