[3H]Citalopram Binding to Brain and Platelet Membranes of Human and Rat

: Citalopram, a selective serotonin (5‐HT) uptake inhibitor with antidepressant properties, was found to bind with high affinity to the 5‐HT transporter from human neuronal and platelet membranes. At 20°C, KD was about 1.5 nM in both tissues. [3H]Citalopram bound to rat neuronal membranes with highe...

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