Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma

Proteolytic enzymes, such as type IV collagenase, play an important role in tumor invasion and metastasis. To examine Mr 72,000 type IV collagenase expression in human colon carcinoma, blot hybridization of total RNA from 19 primary colon tumors were performed. These filters were probed with complem...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1991, Vol.51 (1), p.439-444
Hauptverfasser:	LEVY, A. T, CIOCE, V, SOBEL, M. E, GARBISSA, S, GRIGIONI, W. F, LIOTTA, L. A, STETLER-STEVENSON, W. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - enzymology Amino Acid Sequence Base Sequence Biological and medical sciences Blotting, Northern Cloning, Molecular Collagen - metabolism Colorectal Neoplasms - enzymology Colorectal Neoplasms - genetics DNA - genetics Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Humans Immunohistochemistry Intestinal Mucosa - enzymology Matrix Metalloproteinase 9 Medical sciences Microbial Collagenase - genetics Microbial Collagenase - metabolism Molecular Sequence Data Molecular Weight RNA, Messenger - genetics RNA, Neoplasm - genetics Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Transcription, Genetic Tumors
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