Inhibition of primate spinothalamic tract neurons by stimulation in ventral posterior lateral (VPLc) thalamic nucleus: possible mechanisms
The inhibitory effects of stimulation in the caudal part of the ipsilateral or contralateral ventral posterior lateral (VPL sub(c)) thalamus nucleus were examined in recordings from 52 spinothalamic tract (STT) neurons in the lumbosacral enlargement of anesthetized monkeys. The stimulation site in t...
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| Veröffentlicht in: | Journal of neurophysiology 1983-02, Vol.49 (2), p.406-423 |
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| container_title | Journal of neurophysiology |
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| creator | Gerhart, K D Yezierski, R P Fang, Z R Willis, W D |
| description | The inhibitory effects of stimulation in the caudal part of the ipsilateral or contralateral ventral posterior lateral (VPL sub(c)) thalamus nucleus were examined in recordings from 52 spinothalamic tract (STT) neurons in the lumbosacral enlargement of anesthetized monkeys. The stimulation site in the contralateral VPL sub(c) nucleus was also employed to activate STT cells antidromically and thus, when testing for inhibitory effects, the stimulus strength was kept below the antidromic activation threshold. STT neurons were classified as wide dynamic range (WDR) or high threshold (HT) on the basis of their responses to mechanical stimulation of their cutaneous receptive fields. |
| doi_str_mv | 10.1152/jn.1983.49.2.406 |
| format | Article |
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The stimulation site in the contralateral VPL sub(c) nucleus was also employed to activate STT cells antidromically and thus, when testing for inhibitory effects, the stimulus strength was kept below the antidromic activation threshold. STT neurons were classified as wide dynamic range (WDR) or high threshold (HT) on the basis of their responses to mechanical stimulation of their cutaneous receptive fields.</description><identifier>ISSN: 0022-3077</identifier><identifier>EISSN: 1522-1598</identifier><identifier>DOI: 10.1152/jn.1983.49.2.406</identifier><identifier>PMID: 6834084</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Brain Mapping ; Dominance, Cerebral - physiology ; Electric Stimulation ; Evoked Potentials, Somatosensory ; Forelimb - innervation ; Hindlimb - innervation ; Macaca fascicularis ; Mechanoreceptors - physiology ; Neural Inhibition ; Neurons - physiology ; Nociceptors - physiology ; Reaction Time - physiology ; Space life sciences ; Spinal Cord - physiology ; Spinothalamic Tracts - physiology ; Sural Nerve - physiology ; Thalamic Nuclei - physiology</subject><ispartof>Journal of neurophysiology, 1983-02, Vol.49 (2), p.406-423</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c325t-4e9433e74fd37d7399f20d37ba3e376370f07dbaa159db64022c2080dbf1d4b83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6834084$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gerhart, K D</creatorcontrib><creatorcontrib>Yezierski, R P</creatorcontrib><creatorcontrib>Fang, Z R</creatorcontrib><creatorcontrib>Willis, W D</creatorcontrib><title>Inhibition of primate spinothalamic tract neurons by stimulation in ventral posterior lateral (VPLc) thalamic nucleus: possible mechanisms</title><title>Journal of neurophysiology</title><addtitle>J Neurophysiol</addtitle><description>The inhibitory effects of stimulation in the caudal part of the ipsilateral or contralateral ventral posterior lateral (VPL sub(c)) thalamus nucleus were examined in recordings from 52 spinothalamic tract (STT) neurons in the lumbosacral enlargement of anesthetized monkeys. The stimulation site in the contralateral VPL sub(c) nucleus was also employed to activate STT cells antidromically and thus, when testing for inhibitory effects, the stimulus strength was kept below the antidromic activation threshold. 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| ispartof | Journal of neurophysiology, 1983-02, Vol.49 (2), p.406-423 |
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| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Brain Mapping Dominance, Cerebral - physiology Electric Stimulation Evoked Potentials, Somatosensory Forelimb - innervation Hindlimb - innervation Macaca fascicularis Mechanoreceptors - physiology Neural Inhibition Neurons - physiology Nociceptors - physiology Reaction Time - physiology Space life sciences Spinal Cord - physiology Spinothalamic Tracts - physiology Sural Nerve - physiology Thalamic Nuclei - physiology |
| title | Inhibition of primate spinothalamic tract neurons by stimulation in ventral posterior lateral (VPLc) thalamic nucleus: possible mechanisms |
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