Preparation and evaluation of pyridoxalated-polymerized human hemoglobin

A solution of hemoglobin has several potential applications as a blood substitute. However, because of high oxygen affinity ( P 50 ∼ 14 mm Hg) and short vascular retention time of hemoglobin (plasma half-disappearance time ∼ 3.5 hr), a solution of hemoglobin presents limitations for its general use...

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Veröffentlicht in:	The Journal of surgical research 1983-03, Vol.34 (3), p.205-212
Hauptverfasser:	DeVenuto, Frank, Zegna, Angelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Coagulation Tests Blood Substitutes Chemical Phenomena Chemistry, Physical Crystallization Evaluation Studies as Topic Half-Life Hemoglobins Humans Molecular Weight Pyridoxal Phosphate - analogs & derivatives Rats
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