STUDIES ON BIOSYNTHESIS OF PENTALENOLACTONE. V: ISOLATION OF DEOXYPENTALENYLGLUCURON
Deoxypentalenylglucuron was isolated from the culture broths of three different strains, such as Streptomyces omiyaensis, S. albofaciens and S. viridifaciens. The structure of deoxypentalenylglucuron has been determined by 1H and 13C NMR, mass spectroscopy and by chemical correlation to be an oxidat...
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| Veröffentlicht in: | Journal of antibiotics 1983, Vol.36(3), pp.226-228 |
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| container_end_page | 228 |
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| container_issue | 3 |
| container_start_page | 226 |
| container_title | Journal of antibiotics |
| container_volume | 36 |
| creator | TAKAHASHI, SHUJI TAKEUCHI, MICHIKO ARAI, MAMORU SETO, HARUO OTAKE, NOBORU |
| description | Deoxypentalenylglucuron was isolated from the culture broths of three different strains, such as Streptomyces omiyaensis, S. albofaciens and S. viridifaciens. The structure of deoxypentalenylglucuron has been determined by 1H and 13C NMR, mass spectroscopy and by chemical correlation to be an oxidation product of pentalenene 1. Deoxypentalenylglucuron (1) has some antitumor activity against Sarcoma 180 in mice. |
| doi_str_mv | 10.7164/antibiotics.36.226 |
| format | Article |
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Deoxypentalenylglucuron (1) has some antitumor activity against Sarcoma 180 in mice.</description><identifier>ISSN: 0021-8820</identifier><identifier>EISSN: 1881-1469</identifier><identifier>DOI: 10.7164/antibiotics.36.226</identifier><identifier>PMID: 6833143</identifier><language>eng</language><publisher>Japan: JAPAN ANTIBIOTICS RESEARCH ASSOCIATION</publisher><subject>Animals ; Anti-Bacterial Agents - biosynthesis ; Antibiotics, Antineoplastic - therapeutic use ; Mice ; Oxidation-Reduction ; Sarcoma 180 - drug therapy ; Sesquiterpenes - biosynthesis ; Sesquiterpenes - isolation & purification ; Sesquiterpenes - therapeutic use ; Streptomyces ; Streptomyces - metabolism</subject><ispartof>The Journal of Antibiotics, 1983, Vol.36(3), pp.226-228</ispartof><rights>Japan Antibiotics Research Association</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4226-b86bda257fed9aa88c34b0301fe29c10d8c6dd698fd04332c7ce9f0923f4eefd3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1876,4009,27902,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6833143$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>TAKAHASHI, SHUJI</creatorcontrib><creatorcontrib>TAKEUCHI, MICHIKO</creatorcontrib><creatorcontrib>ARAI, MAMORU</creatorcontrib><creatorcontrib>SETO, HARUO</creatorcontrib><creatorcontrib>OTAKE, NOBORU</creatorcontrib><title>STUDIES ON BIOSYNTHESIS OF PENTALENOLACTONE. 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Deoxypentalenylglucuron (1) has some antitumor activity against Sarcoma 180 in mice.</description><subject>Animals</subject><subject>Anti-Bacterial Agents - biosynthesis</subject><subject>Antibiotics, Antineoplastic - therapeutic use</subject><subject>Mice</subject><subject>Oxidation-Reduction</subject><subject>Sarcoma 180 - drug therapy</subject><subject>Sesquiterpenes - biosynthesis</subject><subject>Sesquiterpenes - isolation & purification</subject><subject>Sesquiterpenes - therapeutic use</subject><subject>Streptomyces</subject><subject>Streptomyces - metabolism</subject><issn>0021-8820</issn><issn>1881-1469</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE9Lw0AQxRdRaq1-AUHIyVvi_utmc6w1tcGQCEkFT8tms9GUtKnZ9OC3d0tK6c3LDMN782PmAXCPoOcjRp_ktq-Luu1rZTzCPIzZBRgjzpGLKAsuwRhCjFzOMbwGN8asISQ-8fkIjBgnBFEyBl6Wr16iMHPSxHmO0uwzyZdhFtl54byHST6LwySNZ_M8TULP-bgFV5VsjL479glYLcJ8vnTj9DWaz2JXUXuFW3BWlBJP_UqXgZScK0ILSCCqNA4UgiVXrCxZwKsSUkKw8pUOKhhgUlGtq5JMwOPA3XXtz16bXmxqo3TTyK1u90ZwSJHPffqvEZFpwKE_tUY8GFXXGtPpSuy6eiO7X4GgOKQpztIUhAn7h116ONL3xUaXp5VjfFZ_G_S16eWXPumys5RGnyNRwPgBS4Zi6SeX-pad0FvyB9b-ifc</recordid><startdate>1983</startdate><enddate>1983</enddate><creator>TAKAHASHI, SHUJI</creator><creator>TAKEUCHI, MICHIKO</creator><creator>ARAI, MAMORU</creator><creator>SETO, HARUO</creator><creator>OTAKE, NOBORU</creator><general>JAPAN ANTIBIOTICS RESEARCH ASSOCIATION</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>1983</creationdate><title>STUDIES ON BIOSYNTHESIS OF PENTALENOLACTONE. 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V: ISOLATION OF DEOXYPENTALENYLGLUCURON</atitle><jtitle>Journal of antibiotics</jtitle><addtitle>J. Antibiot.</addtitle><date>1983</date><risdate>1983</risdate><volume>36</volume><issue>3</issue><spage>226</spage><epage>228</epage><pages>226-228</pages><issn>0021-8820</issn><eissn>1881-1469</eissn><abstract>Deoxypentalenylglucuron was isolated from the culture broths of three different strains, such as Streptomyces omiyaensis, S. albofaciens and S. viridifaciens. The structure of deoxypentalenylglucuron has been determined by 1H and 13C NMR, mass spectroscopy and by chemical correlation to be an oxidation product of pentalenene 1. Deoxypentalenylglucuron (1) has some antitumor activity against Sarcoma 180 in mice.</abstract><cop>Japan</cop><pub>JAPAN ANTIBIOTICS RESEARCH ASSOCIATION</pub><pmid>6833143</pmid><doi>10.7164/antibiotics.36.226</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-8820 |
| ispartof | The Journal of Antibiotics, 1983, Vol.36(3), pp.226-228 |
| issn | 0021-8820 1881-1469 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80417874 |
| source | J-STAGE Free; MEDLINE |
| subjects | Animals Anti-Bacterial Agents - biosynthesis Antibiotics, Antineoplastic - therapeutic use Mice Oxidation-Reduction Sarcoma 180 - drug therapy Sesquiterpenes - biosynthesis Sesquiterpenes - isolation & purification Sesquiterpenes - therapeutic use Streptomyces Streptomyces - metabolism |
| title | STUDIES ON BIOSYNTHESIS OF PENTALENOLACTONE. V: ISOLATION OF DEOXYPENTALENYLGLUCURON |
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