Isotypic profiles and other fine characteristics of immune responses to exogenous thymus-dependent and -independent antigens by mice with lupus syndromes

The authors have now analyzed several aspects of immune responsiveness in SLE strains, compared with age- and allotypematched normal controls, to thymus-independent class 1 and 2 (Tl-1,2) antigens as well as to thymus-dependent (TD) antigens. Results indicate that all SLE strains are hyperresponsive...

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Veröffentlicht in:	The Journal of immunology (1950) 1983-05, Vol.130 (5), p.2161-2167
Hauptverfasser:	Park, C L, Balderas, R S, Fieser, T M, Slack, J H, Prud'Homme, G J, Dixon, F J, Theofilopoulos, A N
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Antibody Affinity Antibody-Producing Cells - immunology Antigens, T-Independent - immunology Female Ficoll - analogs & derivatives Ficoll - immunology Hemocyanins - immunology Hemolytic Plaque Technique Immunoglobulin Allotypes - analysis Immunoglobulin Allotypes - biosynthesis Immunoglobulin Allotypes - immunology Immunoglobulin G - biosynthesis Immunoglobulin G - classification Immunoglobulin G - immunology Kinetics Lipopolysaccharides - immunology Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - mortality Male Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred NZB Rabbits Syndrome Trinitrobenzenes - immunology
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