Glucose-6-Phosphate Dehydrogenase Deficiency in Male Patients with Mediterranean Spotted Fever in Sardinia
The authors reviewed the records of 108 male patients (13-80 years of age) admitted to their department for treatment of Mediterranean spotted fever (MSF), a rickettsial infection that is widespread in the Mediterranean basin. The aim was to see whether the G6PD deficiency was related to more severe...
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| Veröffentlicht in: | The Journal of infectious diseases 1983-03, Vol.147 (3), p.607-608 |
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| container_title | The Journal of infectious diseases |
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| creator | Piras, M. A. Calia, G. Saba, F. Gakis, C. Andreoni, G. |
| description | The authors reviewed the records of 108 male patients (13-80 years of age) admitted to their department for treatment of Mediterranean spotted fever (MSF), a rickettsial infection that is widespread in the Mediterranean basin. The aim was to see whether the G6PD deficiency was related to more severe illness in MSF which is benign and somewhat milder than RMSF. The incidence of complications (90.90%) was significantly higher in subjects who were deficient in G6PD than in subjects with normal G6PD levels. Renal alterations, which affected 80% of those patients with complications, were the most frequent complications, followed by hepatic ones (60%), and cardiovascular and respiratory involvement (both at 50%). |
| doi_str_mv | 10.1093/infdis/147.3.607 |
| format | Article |
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A. ; Calia, G. ; Saba, F. ; Gakis, C. ; Andreoni, G.</creator><creatorcontrib>Piras, M. A. ; Calia, G. ; Saba, F. ; Gakis, C. ; Andreoni, G.</creatorcontrib><description>The authors reviewed the records of 108 male patients (13-80 years of age) admitted to their department for treatment of Mediterranean spotted fever (MSF), a rickettsial infection that is widespread in the Mediterranean basin. The aim was to see whether the G6PD deficiency was related to more severe illness in MSF which is benign and somewhat milder than RMSF. The incidence of complications (90.90%) was significantly higher in subjects who were deficient in G6PD than in subjects with normal G6PD levels. Renal alterations, which affected 80% of those patients with complications, were the most frequent complications, followed by hepatic ones (60%), and cardiovascular and respiratory involvement (both at 50%).</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/147.3.607</identifier><identifier>PMID: 6833807</identifier><language>eng</language><publisher>United States: The University of Chicago Press</publisher><subject>Adolescent ; Adult ; Aged ; Black people ; Boutonneuse fever ; Boutonneuse Fever - complications ; Comment ; Diseases ; Glucosephosphate Dehydrogenase Deficiency - etiology ; Hemolysis ; Humans ; Infectious diseases ; Italy ; Male ; Middle Aged ; Pathology ; Rickettsia ; Rickettsiaceae Infections - complications ; Rocky Mountain spotted fever ; Scrub typhus</subject><ispartof>The Journal of infectious diseases, 1983-03, Vol.147 (3), p.607-608</ispartof><rights>Copyright 1983 The University of Chicago</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c427t-ac519c1b675fdb6ee6c6b5820de38daed7c266a2df95ab90b49f561cd0aea0d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/30119465$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/30119465$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27922,27923,58015,58248</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6833807$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Piras, M. A.</creatorcontrib><creatorcontrib>Calia, G.</creatorcontrib><creatorcontrib>Saba, F.</creatorcontrib><creatorcontrib>Gakis, C.</creatorcontrib><creatorcontrib>Andreoni, G.</creatorcontrib><title>Glucose-6-Phosphate Dehydrogenase Deficiency in Male Patients with Mediterranean Spotted Fever in Sardinia</title><title>The Journal of infectious diseases</title><addtitle>J Infect Dis</addtitle><description>The authors reviewed the records of 108 male patients (13-80 years of age) admitted to their department for treatment of Mediterranean spotted fever (MSF), a rickettsial infection that is widespread in the Mediterranean basin. The aim was to see whether the G6PD deficiency was related to more severe illness in MSF which is benign and somewhat milder than RMSF. The incidence of complications (90.90%) was significantly higher in subjects who were deficient in G6PD than in subjects with normal G6PD levels. Renal alterations, which affected 80% of those patients with complications, were the most frequent complications, followed by hepatic ones (60%), and cardiovascular and respiratory involvement (both at 50%).</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Black people</subject><subject>Boutonneuse fever</subject><subject>Boutonneuse Fever - complications</subject><subject>Comment</subject><subject>Diseases</subject><subject>Glucosephosphate Dehydrogenase Deficiency - etiology</subject><subject>Hemolysis</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Italy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pathology</subject><subject>Rickettsia</subject><subject>Rickettsiaceae Infections - complications</subject><subject>Rocky Mountain spotted fever</subject><subject>Scrub typhus</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcFr2zAUxsVY6dJ2910GPu3m9MmyJPu4dWszaGlpCyu7iGfpeVHm2KmkbM1_P4eE7FgQCL3f93089DH2gcOUQy3Ofd86H895qadiqkC_YRMuhc6V4uItmwAURc6run7HTmJcAEAplD5mx6oSogI9YYurbm2HSLnK7-ZDXM0xUfaV5hsXhl_UY9y-Wm899XaT-T67wY6yO0zjIMXsr0_z7IacTxQC9oR99rAaUiKXXdIfClvHAwbne49n7KjFLtL7_X3KHi-_PV7M8uvbq-8Xn69zWxY65Wglry1vlJataxSRsqqRVQGOROWQnLaFUli4tpbY1NCUdSsVtw6QEJw4ZZ92saswPK8pJrP00VLXjesN62gqKDloAa8KuZCVGs8ohJ3QhiHGQK1ZBb_EsDEczLYGs6vBjDUYYcYaRsvHffa6WZI7GPb__p8vYhrCAQvgvC6VHHm-4z4mejlwDL-N0kJLM3v6ab5UTz9gds_NvfgH8QCfcQ</recordid><startdate>198303</startdate><enddate>198303</enddate><creator>Piras, M. A.</creator><creator>Calia, G.</creator><creator>Saba, F.</creator><creator>Gakis, C.</creator><creator>Andreoni, G.</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>198303</creationdate><title>Glucose-6-Phosphate Dehydrogenase Deficiency in Male Patients with Mediterranean Spotted Fever in Sardinia</title><author>Piras, M. A. ; Calia, G. ; Saba, F. ; Gakis, C. ; Andreoni, G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c427t-ac519c1b675fdb6ee6c6b5820de38daed7c266a2df95ab90b49f561cd0aea0d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Black people</topic><topic>Boutonneuse fever</topic><topic>Boutonneuse Fever - complications</topic><topic>Comment</topic><topic>Diseases</topic><topic>Glucosephosphate Dehydrogenase Deficiency - etiology</topic><topic>Hemolysis</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Italy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pathology</topic><topic>Rickettsia</topic><topic>Rickettsiaceae Infections - complications</topic><topic>Rocky Mountain spotted fever</topic><topic>Scrub typhus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Piras, M. A.</creatorcontrib><creatorcontrib>Calia, G.</creatorcontrib><creatorcontrib>Saba, F.</creatorcontrib><creatorcontrib>Gakis, C.</creatorcontrib><creatorcontrib>Andreoni, G.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Piras, M. 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The incidence of complications (90.90%) was significantly higher in subjects who were deficient in G6PD than in subjects with normal G6PD levels. Renal alterations, which affected 80% of those patients with complications, were the most frequent complications, followed by hepatic ones (60%), and cardiovascular and respiratory involvement (both at 50%).</abstract><cop>United States</cop><pub>The University of Chicago Press</pub><pmid>6833807</pmid><doi>10.1093/infdis/147.3.607</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1899 |
| ispartof | The Journal of infectious diseases, 1983-03, Vol.147 (3), p.607-608 |
| issn | 0022-1899 1537-6613 |
| language | eng |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing |
| subjects | Adolescent Adult Aged Black people Boutonneuse fever Boutonneuse Fever - complications Comment Diseases Glucosephosphate Dehydrogenase Deficiency - etiology Hemolysis Humans Infectious diseases Italy Male Middle Aged Pathology Rickettsia Rickettsiaceae Infections - complications Rocky Mountain spotted fever Scrub typhus |
| title | Glucose-6-Phosphate Dehydrogenase Deficiency in Male Patients with Mediterranean Spotted Fever in Sardinia |
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