Inhibition of soybean lipoxygenase by sulfasalazine and 5-aminosalicylic acid: a possible mode of action in ulcerative colitis

Leukotrienes, hydroperoxyeicosatetraenoic acids (HPETE), and hydroxyeicostetraenoic acids (HETE) are products of arachidonic acid metabolism via the lipoxygenase pathway. They have been shown to be highly potent and stereospecific factors stimulating polymorphonuclear leukocyte (PMNL) migration and...

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Veröffentlicht in:	Biochemical pharmacology 1983, Vol.32 (1), p.170-172
Hauptverfasser:	Sircar, Jagadish C., Schwender, Charles F., Carethers, Mary E.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-aminosalicyclic acid Aminosalicylic Acids - pharmacology Colitis, Ulcerative - drug therapy Glycine max Glycine max - enzymology Humans Kinetics lipoxygenase Lipoxygenase Inhibitors Mesalamine sulfasalazine Sulfasalazine - pharmacology
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