An idiotypic determinant formed by both immunoglobulin constant and variable regions

Immunoglobulin idiotypes are serologically defined determinants associated with the variable (V) region of antibody molecules (reviewed in refs 1–4). One of the best defined idiotype systems is that borne by the phosphorylcholine (PC)-binding IgA proteins TEPC15 (T15) and HOPC8 (H8) 5 . The T15 idio...

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Veröffentlicht in:	Nature (London) 1983-02, Vol.301 (5902), p.720-722
Hauptverfasser:	Morahan, Grant, Berek, Claudia, Miller, J. F. A. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Antibody Specificity Binding Sites, Antibody - genetics Epitopes Humanities and Social Sciences Immunoglobulin Constant Regions - genetics Immunoglobulin Idiotypes - genetics Immunoglobulin Variable Region - genetics Immunoglobulins - genetics letter Mice multidisciplinary Protein Conformation Science Science (multidisciplinary)
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