Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children
The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is re...
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| Veröffentlicht in: | Am. J. Cardiol.; (United States) 1983-01, Vol.51 (2), p.261-264 |
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| container_title | Am. J. Cardiol.; (United States) |
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| creator | Parrish, Mark D. Graham, Thomas P. Born, Mark L. Jones, Jerome P. Boucek, Robert J. Artman, Michael Partain, C. Leon |
| description | The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal—40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload—13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload—7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p |
| doi_str_mv | 10.1016/S0002-9149(83)80046-0 |
| format | Article |
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Leon</creator><creatorcontrib>Parrish, Mark D. ; Graham, Thomas P. ; Born, Mark L. ; Jones, Jerome P. ; Boucek, Robert J. ; Artman, Michael ; Partain, C. Leon ; Department of Pediatrics, Vanderbilt University Hospital, Nashville, Tennessee</creatorcontrib><description>The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal—40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload—13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload—7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/S0002-9149(83)80046-0</identifier><identifier>PMID: 6823834</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics ; Adolescent ; AGE GROUPS ; Aortic Valve Insufficiency - diagnostic imaging ; BETA DECAY RADIOISOTOPES ; BETA-MINUS DECAY RADIOISOTOPES ; BLOOD CIRCULATION ; CARDIOGRAPHY ; CARDIOVASCULAR DISEASES ; Child ; Child, Preschool ; CHILDREN ; DIAGNOSIS ; DIAGNOSTIC TECHNIQUES ; DIAGNOSTIC USES ; DISEASES ; Erythrocytes ; Heart - diagnostic imaging ; Heart Defects, Congenital - diagnostic imaging ; Heart Septal Defects, Atrial - diagnostic imaging ; HOURS LIVING RADIOISOTOPES ; Humans ; Infant ; INTERMEDIATE MASS NUCLEI ; ISOMERIC NUCLEI ; ISOMERIC TRANSITION ISOTOPES ; ISOTOPES ; MEDICINE ; Mitral Valve Insufficiency - diagnostic imaging ; NUCLEI ; ODD-EVEN NUCLEI ; PATIENTS ; PEDIATRICS ; RADIOCARDIOGRAPHY ; RADIOISOTOPES ; RADIOLOGY AND NUCLEAR MEDICINE ; Radionuclide Imaging ; Stroke Volume ; TECHNETIUM 99 ; TECHNETIUM ISOTOPES ; Tetralogy of Fallot - diagnostic imaging ; Transposition of Great Vessels - diagnostic imaging ; USES ; VOLUME ; YEARS LIVING RADIOISOTOPES</subject><ispartof>Am. 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Cardiol.; (United States), 1983-01, Vol.51 (2), p.261-264</ispartof><rights>1983</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-550ffa2c3d28b5fd04a7a9bc6d540a2f64ad0568db9947a008ac217390f6ed483</citedby><cites>FETCH-LOGICAL-c387t-550ffa2c3d28b5fd04a7a9bc6d540a2f64ad0568db9947a008ac217390f6ed483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0002-9149(83)80046-0$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,882,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6823834$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6257172$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Parrish, Mark D.</creatorcontrib><creatorcontrib>Graham, Thomas P.</creatorcontrib><creatorcontrib>Born, Mark L.</creatorcontrib><creatorcontrib>Jones, Jerome P.</creatorcontrib><creatorcontrib>Boucek, Robert J.</creatorcontrib><creatorcontrib>Artman, Michael</creatorcontrib><creatorcontrib>Partain, C. Leon</creatorcontrib><creatorcontrib>Department of Pediatrics, Vanderbilt University Hospital, Nashville, Tennessee</creatorcontrib><title>Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children</title><title>Am. J. Cardiol.; (United States)</title><addtitle>Am J Cardiol</addtitle><description>The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal—40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload—13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload—7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.</description><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics</subject><subject>Adolescent</subject><subject>AGE GROUPS</subject><subject>Aortic Valve Insufficiency - diagnostic imaging</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>BETA-MINUS DECAY RADIOISOTOPES</subject><subject>BLOOD CIRCULATION</subject><subject>CARDIOGRAPHY</subject><subject>CARDIOVASCULAR DISEASES</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>CHILDREN</subject><subject>DIAGNOSIS</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DIAGNOSTIC USES</subject><subject>DISEASES</subject><subject>Erythrocytes</subject><subject>Heart - diagnostic imaging</subject><subject>Heart Defects, Congenital - diagnostic imaging</subject><subject>Heart Septal Defects, Atrial - diagnostic imaging</subject><subject>HOURS LIVING RADIOISOTOPES</subject><subject>Humans</subject><subject>Infant</subject><subject>INTERMEDIATE MASS NUCLEI</subject><subject>ISOMERIC NUCLEI</subject><subject>ISOMERIC TRANSITION ISOTOPES</subject><subject>ISOTOPES</subject><subject>MEDICINE</subject><subject>Mitral Valve Insufficiency - diagnostic imaging</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>PATIENTS</subject><subject>PEDIATRICS</subject><subject>RADIOCARDIOGRAPHY</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radionuclide Imaging</subject><subject>Stroke Volume</subject><subject>TECHNETIUM 99</subject><subject>TECHNETIUM ISOTOPES</subject><subject>Tetralogy of Fallot - diagnostic imaging</subject><subject>Transposition of Great Vessels - diagnostic imaging</subject><subject>USES</subject><subject>VOLUME</subject><subject>YEARS LIVING RADIOISOTOPES</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2LFDEQhoMo67j6ExaCB9FDa6WTTqdPIotfsCD4cQ6ZpOJE08mapAf893bvDHv1VFTVUx-8LyFXDF4zYPLNNwDou4mJ6aXirxSAkB08IDumxqljE-MPye4eeUye1PprTRkb5AW5kKrniosdCV-NCzktNgaHtLaSfyO1eUmNFtNCrtTnQk2tWOuMazV7WsLPQ6MmORrRN3pcyyXYJZpCjzkuM9J8xBKzcTQkag8huoLpKXnkTaz47BwvyY8P779ff-puvnz8fP3uprNcja0bBvDe9Ja7Xu0H70CY0Ux7K90gwPReCuNgkMrtp0mMBkAZ27ORT-AlOqH4JXl-2ptrC7ra0NAebE4JbdOyH0Y29iv04gTdlvxnwdr0HKrFGE3CvFStgI-sF7CCwwm0Jdda0OvbEmZT_moGevNB3_mgN5G14vrOB73NXZ0PLPsZ3f3UWfi1__bUx1WKY8CyfYrJogtle9Tl8J8L_wBY45jo</recordid><startdate>19830115</startdate><enddate>19830115</enddate><creator>Parrish, Mark D.</creator><creator>Graham, Thomas P.</creator><creator>Born, Mark L.</creator><creator>Jones, Jerome P.</creator><creator>Boucek, Robert J.</creator><creator>Artman, Michael</creator><creator>Partain, C. Leon</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>19830115</creationdate><title>Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children</title><author>Parrish, Mark D. ; Graham, Thomas P. ; Born, Mark L. ; Jones, Jerome P. ; Boucek, Robert J. ; Artman, Michael ; Partain, C. Leon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-550ffa2c3d28b5fd04a7a9bc6d540a2f64ad0568db9947a008ac217390f6ed483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>550601 - Medicine- Unsealed Radionuclides in Diagnostics</topic><topic>Adolescent</topic><topic>AGE GROUPS</topic><topic>Aortic Valve Insufficiency - diagnostic imaging</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BETA-MINUS DECAY RADIOISOTOPES</topic><topic>BLOOD CIRCULATION</topic><topic>CARDIOGRAPHY</topic><topic>CARDIOVASCULAR DISEASES</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>CHILDREN</topic><topic>DIAGNOSIS</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DIAGNOSTIC USES</topic><topic>DISEASES</topic><topic>Erythrocytes</topic><topic>Heart - diagnostic imaging</topic><topic>Heart Defects, Congenital - diagnostic imaging</topic><topic>Heart Septal Defects, Atrial - diagnostic imaging</topic><topic>HOURS LIVING RADIOISOTOPES</topic><topic>Humans</topic><topic>Infant</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>ISOMERIC NUCLEI</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>MEDICINE</topic><topic>Mitral Valve Insufficiency - diagnostic imaging</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>PATIENTS</topic><topic>PEDIATRICS</topic><topic>RADIOCARDIOGRAPHY</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide Imaging</topic><topic>Stroke Volume</topic><topic>TECHNETIUM 99</topic><topic>TECHNETIUM ISOTOPES</topic><topic>Tetralogy of Fallot - diagnostic imaging</topic><topic>Transposition of Great Vessels - diagnostic imaging</topic><topic>USES</topic><topic>VOLUME</topic><topic>YEARS LIVING RADIOISOTOPES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parrish, Mark D.</creatorcontrib><creatorcontrib>Graham, Thomas P.</creatorcontrib><creatorcontrib>Born, Mark L.</creatorcontrib><creatorcontrib>Jones, Jerome P.</creatorcontrib><creatorcontrib>Boucek, Robert J.</creatorcontrib><creatorcontrib>Artman, Michael</creatorcontrib><creatorcontrib>Partain, C. Leon</creatorcontrib><creatorcontrib>Department of Pediatrics, Vanderbilt University Hospital, Nashville, Tennessee</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Am. J. Cardiol.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Parrish, Mark D.</au><au>Graham, Thomas P.</au><au>Born, Mark L.</au><au>Jones, Jerome P.</au><au>Boucek, Robert J.</au><au>Artman, Michael</au><au>Partain, C. Leon</au><aucorp>Department of Pediatrics, Vanderbilt University Hospital, Nashville, Tennessee</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children</atitle><jtitle>Am. J. Cardiol.; (United States)</jtitle><addtitle>Am J Cardiol</addtitle><date>1983-01-15</date><risdate>1983</risdate><volume>51</volume><issue>2</issue><spage>261</spage><epage>264</epage><pages>261-264</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><abstract>The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal—40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload—13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload—7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>6823834</pmid><doi>10.1016/S0002-9149(83)80046-0</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9149 |
| ispartof | Am. J. Cardiol.; (United States), 1983-01, Vol.51 (2), p.261-264 |
| issn | 0002-9149 1879-1913 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80371240 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | 550601 - Medicine- Unsealed Radionuclides in Diagnostics Adolescent AGE GROUPS Aortic Valve Insufficiency - diagnostic imaging BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES BLOOD CIRCULATION CARDIOGRAPHY CARDIOVASCULAR DISEASES Child Child, Preschool CHILDREN DIAGNOSIS DIAGNOSTIC TECHNIQUES DIAGNOSTIC USES DISEASES Erythrocytes Heart - diagnostic imaging Heart Defects, Congenital - diagnostic imaging Heart Septal Defects, Atrial - diagnostic imaging HOURS LIVING RADIOISOTOPES Humans Infant INTERMEDIATE MASS NUCLEI ISOMERIC NUCLEI ISOMERIC TRANSITION ISOTOPES ISOTOPES MEDICINE Mitral Valve Insufficiency - diagnostic imaging NUCLEI ODD-EVEN NUCLEI PATIENTS PEDIATRICS RADIOCARDIOGRAPHY RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE Radionuclide Imaging Stroke Volume TECHNETIUM 99 TECHNETIUM ISOTOPES Tetralogy of Fallot - diagnostic imaging Transposition of Great Vessels - diagnostic imaging USES VOLUME YEARS LIVING RADIOISOTOPES |
| title | Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children |
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