A randomized controlled trial of allopurinol in coronary bypass surgery

A plethora of experimental evidence indicates that allopurinol reduces the formation of cytotoxic free radicals during myocardial ischemia and reperfusion. The purpose of this study was to evaluate the effect of allopurinol on cardiac performance and early mortality after coronary bypass surgery. Al...

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Veröffentlicht in:	The American heart journal 1991-01, Vol.121 (1), p.20-24
Hauptverfasser:	Johnson, W. Dudley, Kayser, Kenneth L., Brenowitz, Jerold B., Saedi, Saed F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Allopurinol - therapeutic use Biological and medical sciences Cardiology. Vascular system Cause of Death Coronary Artery Bypass - mortality Coronary Disease - mortality Coronary Disease - physiopathology Coronary Disease - surgery Coronary heart disease Heart Heart - drug effects Heart - physiopathology Humans Medical sciences Middle Aged Myocardial Reperfusion Injury - prevention & control Postoperative Complications Postoperative Period Premedication
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