Sonography in neonatal congenital adrenal hyperplasia
Adrenal gland size was evaluated in six infants with congenital adrenal hyperplasia. All of the infants had a severe deficiency of the 21-hydroxylase enzyme resulting in the salt-losing form of congenital adrenal hyperplasia. The adrenal measurements were compared with those of 40 consecutive age-ma...
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| Veröffentlicht in: | American journal of roentgenology (1976) 1991-01, Vol.156 (1), p.141-143 |
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| container_title | American journal of roentgenology (1976) |
| container_volume | 156 |
| creator | Sivit, CJ Hung, W Taylor, GA Catena, LM Brown-Jones, C Kushner, DC |
| description | Adrenal gland size was evaluated in six infants with congenital adrenal hyperplasia. All of the infants had a severe deficiency of the 21-hydroxylase enzyme resulting in the salt-losing form of congenital adrenal hyperplasia. The adrenal measurements were compared with those of 40 consecutive age-matched, asymptomatic infants. Mean adrenal length was 14.4 mm and width was 1.9 mm in asymptomatic infants, whereas in infants with congenital adrenal hyperplasia mean adrenal length was 23.7 mm and width was 5.3 mm. Although infants with congenital adrenal hyperplasia may have normal-sized adrenal glands, mean length measurements of 20 mm or greater and mean width measurements of 4 mm or greater suggest the diagnosis. |
| doi_str_mv | 10.2214/ajr.156.1.1898548 |
| format | Article |
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All of the infants had a severe deficiency of the 21-hydroxylase enzyme resulting in the salt-losing form of congenital adrenal hyperplasia. The adrenal measurements were compared with those of 40 consecutive age-matched, asymptomatic infants. Mean adrenal length was 14.4 mm and width was 1.9 mm in asymptomatic infants, whereas in infants with congenital adrenal hyperplasia mean adrenal length was 23.7 mm and width was 5.3 mm. 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All of the infants had a severe deficiency of the 21-hydroxylase enzyme resulting in the salt-losing form of congenital adrenal hyperplasia. The adrenal measurements were compared with those of 40 consecutive age-matched, asymptomatic infants. Mean adrenal length was 14.4 mm and width was 1.9 mm in asymptomatic infants, whereas in infants with congenital adrenal hyperplasia mean adrenal length was 23.7 mm and width was 5.3 mm. 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All of the infants had a severe deficiency of the 21-hydroxylase enzyme resulting in the salt-losing form of congenital adrenal hyperplasia. The adrenal measurements were compared with those of 40 consecutive age-matched, asymptomatic infants. Mean adrenal length was 14.4 mm and width was 1.9 mm in asymptomatic infants, whereas in infants with congenital adrenal hyperplasia mean adrenal length was 23.7 mm and width was 5.3 mm. Although infants with congenital adrenal hyperplasia may have normal-sized adrenal glands, mean length measurements of 20 mm or greater and mean width measurements of 4 mm or greater suggest the diagnosis.</abstract><cop>Leesburg, VA</cop><pub>Am Roentgen Ray Soc</pub><pmid>1898548</pmid><doi>10.2214/ajr.156.1.1898548</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0361-803X |
| ispartof | American journal of roentgenology (1976), 1991-01, Vol.156 (1), p.141-143 |
| issn | 0361-803X 1546-3141 |
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| source | American Roentgen Ray Society; MEDLINE; Alma/SFX Local Collection |
| subjects | Adrenal Glands - diagnostic imaging Adrenal Hyperplasia, Congenital - diagnostic imaging Adrenal Hyperplasia, Congenital - enzymology Biological and medical sciences Endocrine glands Female Humans Infant, Newborn Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Ultrasonic investigative techniques Ultrasonography |
| title | Sonography in neonatal congenital adrenal hyperplasia |
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