Radioimmunoassay of serum prostatic acid phosphatase after prostatic massage
The effect of prostatic massage on the concentration of prostatic acid phosphatase (PAP) in blood serum as determined by radioimmunoassay (RIA) was compared with that determined by a standard enzymatic assay (EA). Serum was drawn from 24 men before prostatic massage and after—at specified intervals,...
Gespeichert in:
| Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 1983, Vol.21 (1), p.37-41 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 41 |
|---|---|
| container_issue | 1 |
| container_start_page | 37 |
| container_title | Urology (Ridgewood, N.J.) |
| container_volume | 21 |
| creator | Pearson, John C. Dombrovskis, Skai Dreyer, Jon Williams, Richard D. |
| description | The effect of prostatic massage on the concentration of prostatic acid phosphatase (PAP) in blood serum as determined by radioimmunoassay (RIA) was compared with that determined by a standard enzymatic assay (EA). Serum was drawn from 24 men before prostatic massage and after—at specified intervals, up to twenty-four hours. Three of these men were young, normal controls; 10 had biopsy-proved prostate cancer (CA); 11 had histologically confirmed benign prostatic hyperplasia (BPH). After prostatic massage, 3 of the 10 CA patients (30%) had elevation of PAP as determined by EA and 4 of the 11 BPH patients (36%) as determined by RIA. None of the controls showed elevated levels of PAP by either assay. In all patients elevated levels of PAP by both assays had returned to normal twenty-four hours after massage. It was concluded that serum for PAP testing by either assay method should be drawn before or twenty-four hours after rectal examination to prevent false positive results and the need for retesting. |
| doi_str_mv | 10.1016/0090-4295(83)90119-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80362651</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>009042958390119X</els_id><sourcerecordid>80362651</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357t-ff33626cda0427fd3b22529f5c3d9617d2d8d8fa0f0cd497b1ad6600861e7cc13</originalsourceid><addsrcrecordid>eNp9kEtLxDAQx4Mo6_r4Bgo9iR6qk6RNm4sgiy9YEERhbyGbTNzIdluTVthvb-suiydPc_g_ZuZHyBmFawpU3ABISDMm88uSX0mgVKazPTKmOStSKWW-T8Y7yyE5ivETAIQQxYiMBC0FiGxMpq_a-tpXVbeqdYx6ndQuiRi6KmlCHVvdepNo423SLOrYLHSrIybatRj-GKoh-oEn5MDpZcTT7Twm7w_3b5OndPry-Dy5m6aG50WbOse5YMJYDRkrnOVzxnImXW64lYIWltnSlk6DA2MzWcyptkIAlIJiYQzlx-Ri09tf8NVhbFXlo8HlUq-w7qIqYejPB2O2MZr-1BjQqSb4Soe1oqAGiGogpAZCquTqF6Ka9bHzbX83r9DuQltqvX670bF_8ttjUNF4XBm0PqBpla39_wt-AJuIgjY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80362651</pqid></control><display><type>article</type><title>Radioimmunoassay of serum prostatic acid phosphatase after prostatic massage</title><source>Elsevier ScienceDirect Journals Complete - AutoHoldings</source><source>MEDLINE</source><creator>Pearson, John C. ; Dombrovskis, Skai ; Dreyer, Jon ; Williams, Richard D.</creator><creatorcontrib>Pearson, John C. ; Dombrovskis, Skai ; Dreyer, Jon ; Williams, Richard D.</creatorcontrib><description>The effect of prostatic massage on the concentration of prostatic acid phosphatase (PAP) in blood serum as determined by radioimmunoassay (RIA) was compared with that determined by a standard enzymatic assay (EA). Serum was drawn from 24 men before prostatic massage and after—at specified intervals, up to twenty-four hours. Three of these men were young, normal controls; 10 had biopsy-proved prostate cancer (CA); 11 had histologically confirmed benign prostatic hyperplasia (BPH). After prostatic massage, 3 of the 10 CA patients (30%) had elevation of PAP as determined by EA and 4 of the 11 BPH patients (36%) as determined by RIA. None of the controls showed elevated levels of PAP by either assay. In all patients elevated levels of PAP by both assays had returned to normal twenty-four hours after massage. It was concluded that serum for PAP testing by either assay method should be drawn before or twenty-four hours after rectal examination to prevent false positive results and the need for retesting.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/0090-4295(83)90119-X</identifier><identifier>PMID: 6186064</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acid Phosphatase - blood ; Adult ; Biopsy ; Clinical Enzyme Tests ; False Positive Reactions ; Humans ; Male ; Massage ; Physical Examination ; Prostate - enzymology ; Prostatic Hyperplasia - enzymology ; Prostatic Hyperplasia - pathology ; Prostatic Neoplasms - diagnosis ; Prostatic Neoplasms - pathology ; Radioimmunoassay ; Time Factors</subject><ispartof>Urology (Ridgewood, N.J.), 1983, Vol.21 (1), p.37-41</ispartof><rights>1983</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-ff33626cda0427fd3b22529f5c3d9617d2d8d8fa0f0cd497b1ad6600861e7cc13</citedby><cites>FETCH-LOGICAL-c357t-ff33626cda0427fd3b22529f5c3d9617d2d8d8fa0f0cd497b1ad6600861e7cc13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0090-4295(83)90119-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,4012,27910,27911,27912,45982</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6186064$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pearson, John C.</creatorcontrib><creatorcontrib>Dombrovskis, Skai</creatorcontrib><creatorcontrib>Dreyer, Jon</creatorcontrib><creatorcontrib>Williams, Richard D.</creatorcontrib><title>Radioimmunoassay of serum prostatic acid phosphatase after prostatic massage</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>The effect of prostatic massage on the concentration of prostatic acid phosphatase (PAP) in blood serum as determined by radioimmunoassay (RIA) was compared with that determined by a standard enzymatic assay (EA). Serum was drawn from 24 men before prostatic massage and after—at specified intervals, up to twenty-four hours. Three of these men were young, normal controls; 10 had biopsy-proved prostate cancer (CA); 11 had histologically confirmed benign prostatic hyperplasia (BPH). After prostatic massage, 3 of the 10 CA patients (30%) had elevation of PAP as determined by EA and 4 of the 11 BPH patients (36%) as determined by RIA. None of the controls showed elevated levels of PAP by either assay. In all patients elevated levels of PAP by both assays had returned to normal twenty-four hours after massage. It was concluded that serum for PAP testing by either assay method should be drawn before or twenty-four hours after rectal examination to prevent false positive results and the need for retesting.</description><subject>Acid Phosphatase - blood</subject><subject>Adult</subject><subject>Biopsy</subject><subject>Clinical Enzyme Tests</subject><subject>False Positive Reactions</subject><subject>Humans</subject><subject>Male</subject><subject>Massage</subject><subject>Physical Examination</subject><subject>Prostate - enzymology</subject><subject>Prostatic Hyperplasia - enzymology</subject><subject>Prostatic Hyperplasia - pathology</subject><subject>Prostatic Neoplasms - diagnosis</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Radioimmunoassay</subject><subject>Time Factors</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAQx4Mo6_r4Bgo9iR6qk6RNm4sgiy9YEERhbyGbTNzIdluTVthvb-suiydPc_g_ZuZHyBmFawpU3ABISDMm88uSX0mgVKazPTKmOStSKWW-T8Y7yyE5ivETAIQQxYiMBC0FiGxMpq_a-tpXVbeqdYx6ndQuiRi6KmlCHVvdepNo423SLOrYLHSrIybatRj-GKoh-oEn5MDpZcTT7Twm7w_3b5OndPry-Dy5m6aG50WbOse5YMJYDRkrnOVzxnImXW64lYIWltnSlk6DA2MzWcyptkIAlIJiYQzlx-Ri09tf8NVhbFXlo8HlUq-w7qIqYejPB2O2MZr-1BjQqSb4Soe1oqAGiGogpAZCquTqF6Ka9bHzbX83r9DuQltqvX670bF_8ttjUNF4XBm0PqBpla39_wt-AJuIgjY</recordid><startdate>1983</startdate><enddate>1983</enddate><creator>Pearson, John C.</creator><creator>Dombrovskis, Skai</creator><creator>Dreyer, Jon</creator><creator>Williams, Richard D.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1983</creationdate><title>Radioimmunoassay of serum prostatic acid phosphatase after prostatic massage</title><author>Pearson, John C. ; Dombrovskis, Skai ; Dreyer, Jon ; Williams, Richard D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-ff33626cda0427fd3b22529f5c3d9617d2d8d8fa0f0cd497b1ad6600861e7cc13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Acid Phosphatase - blood</topic><topic>Adult</topic><topic>Biopsy</topic><topic>Clinical Enzyme Tests</topic><topic>False Positive Reactions</topic><topic>Humans</topic><topic>Male</topic><topic>Massage</topic><topic>Physical Examination</topic><topic>Prostate - enzymology</topic><topic>Prostatic Hyperplasia - enzymology</topic><topic>Prostatic Hyperplasia - pathology</topic><topic>Prostatic Neoplasms - diagnosis</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Radioimmunoassay</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pearson, John C.</creatorcontrib><creatorcontrib>Dombrovskis, Skai</creatorcontrib><creatorcontrib>Dreyer, Jon</creatorcontrib><creatorcontrib>Williams, Richard D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pearson, John C.</au><au>Dombrovskis, Skai</au><au>Dreyer, Jon</au><au>Williams, Richard D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radioimmunoassay of serum prostatic acid phosphatase after prostatic massage</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>1983</date><risdate>1983</risdate><volume>21</volume><issue>1</issue><spage>37</spage><epage>41</epage><pages>37-41</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><abstract>The effect of prostatic massage on the concentration of prostatic acid phosphatase (PAP) in blood serum as determined by radioimmunoassay (RIA) was compared with that determined by a standard enzymatic assay (EA). Serum was drawn from 24 men before prostatic massage and after—at specified intervals, up to twenty-four hours. Three of these men were young, normal controls; 10 had biopsy-proved prostate cancer (CA); 11 had histologically confirmed benign prostatic hyperplasia (BPH). After prostatic massage, 3 of the 10 CA patients (30%) had elevation of PAP as determined by EA and 4 of the 11 BPH patients (36%) as determined by RIA. None of the controls showed elevated levels of PAP by either assay. In all patients elevated levels of PAP by both assays had returned to normal twenty-four hours after massage. It was concluded that serum for PAP testing by either assay method should be drawn before or twenty-four hours after rectal examination to prevent false positive results and the need for retesting.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>6186064</pmid><doi>10.1016/0090-4295(83)90119-X</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0090-4295 |
| ispartof | Urology (Ridgewood, N.J.), 1983, Vol.21 (1), p.37-41 |
| issn | 0090-4295 1527-9995 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80362651 |
| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
| subjects | Acid Phosphatase - blood Adult Biopsy Clinical Enzyme Tests False Positive Reactions Humans Male Massage Physical Examination Prostate - enzymology Prostatic Hyperplasia - enzymology Prostatic Hyperplasia - pathology Prostatic Neoplasms - diagnosis Prostatic Neoplasms - pathology Radioimmunoassay Time Factors |
| title | Radioimmunoassay of serum prostatic acid phosphatase after prostatic massage |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T05%3A52%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Radioimmunoassay%20of%20serum%20prostatic%20acid%20phosphatase%20after%20prostatic%20massage&rft.jtitle=Urology%20(Ridgewood,%20N.J.)&rft.au=Pearson,%20John%20C.&rft.date=1983&rft.volume=21&rft.issue=1&rft.spage=37&rft.epage=41&rft.pages=37-41&rft.issn=0090-4295&rft.eissn=1527-9995&rft_id=info:doi/10.1016/0090-4295(83)90119-X&rft_dat=%3Cproquest_cross%3E80362651%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80362651&rft_id=info:pmid/6186064&rft_els_id=009042958390119X&rfr_iscdi=true |