Igh-V or closely linked gene(s) control immunological memory to a thymus-independent antigen

Mice mount a normal primary antibody response on stimulation with the thymic-independent antigen trinitrophenylated lipopolysaccharide (TNP-LPS). Although we have previously reported the generation of functional B-memory lymphocytes to TNP-LPS, this memory response was only observed in few mouse str...

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Veröffentlicht in:	Nature (London) 1983-02, Vol.301 (5899), p.428-429
Hauptverfasser:	Colle, J-H, Motta, I, Shidani, B, Truffa-Bachi, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites, Antibody - genetics Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Genetics of the immune response Immunobiology Immunoglobulin Heavy Chains - genetics Immunoglobulin Variable Region - genetics Immunologic Memory Lipopolysaccharides - immunology Mice Mice, Inbred Strains Nitrobenzenes - immunology Trinitrobenzenes - immunology
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