Metastases of thin melanomas

Although thin malignant melanomas, i.e., those less than 0.76 mm in thickness, of the skin generally do not metastasize, it has been recently reported that when histologic regression is present, such lesions may then have a greater propensity for dissemination. However, this was not apparent in this...

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Veröffentlicht in:Cancer 1983-02, Vol.51 (3), p.553-556
Hauptverfasser: Trau, Henri, Rigel, Darrell S., Harris, Matthew N., Kopf, Alfred W., Friedman, Robert J., Gumport, Stephen L., Bart, Robert S., Grier, W. Robson N.
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Sprache:eng
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Zusammenfassung:Although thin malignant melanomas, i.e., those less than 0.76 mm in thickness, of the skin generally do not metastasize, it has been recently reported that when histologic regression is present, such lesions may then have a greater propensity for dissemination. However, this was not apparent in this study in which only one melanoma metastasized in a consecutive series of 41 thin lesions which were stepsectioned and had evidence of regression histologically. Possible explanations for this discrepancy are the failure of other authors to include only step‐sectioned specimens of the primary melanomas in their material and/or geographic differences in the biologic behavior of this malignant neoplasm.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19830201)51:3<553::AID-CNCR2820510332>3.0.CO;2-T