The somnogenic T lymphocyte suppressor prostaglandin D2 is selectively elevated in cerebrospinal fluid of advanced sleeping sickness patients

To help to elucidate the changes induced by Trypanosoma brucei gambiense in the central nervous system (CNS) in advanced sleeping sickness patients, levels of interleukin-1 (IL-1) and prostaglandins D2 (PGD2) and E2 (PGE2) were measured by radioimmunoassay in the cerebrospinal fluid (CSF) from 24 pa...

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Veröffentlicht in:Transactions of the Royal Society of Tropical Medicine and Hygiene 1990-11, Vol.84 (6), p.795-799
Hauptverfasser: Pentreath, V.W., Rees, K., Owolabi, O.A., Philip, K.A., Doua, F.
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Sprache:eng
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