Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes
Membranes and solubilized, reconstituted membranes from Moloney-infected tumors MBL-2 have been used to stimulate in vitro secondary cytolytic T lymphocytes (CTL) in C57BL/6 mice primed and Moloney murine sarcoma virus. Membranes are shown to stimulate the generation of Moloney-specific and H-2 rest...
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| Veröffentlicht in: | The Journal of immunology (1950) 1983-01, Vol.130 (1), p.493-495 |
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| container_end_page | 495 |
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| container_issue | 1 |
| container_start_page | 493 |
| container_title | The Journal of immunology (1950) |
| container_volume | 130 |
| creator | Duprez, V Mescher, MF Burakoff, SJ |
| description | Membranes and solubilized, reconstituted membranes from Moloney-infected tumors MBL-2 have been used to stimulate in vitro secondary cytolytic T lymphocytes (CTL) in C57BL/6 mice primed and Moloney murine sarcoma virus. Membranes are shown to stimulate the generation of Moloney-specific and H-2 restricted CTL. Stimulation with solubilized, reconstituted membranes required the presence of rat lymphocyte Con A supernatant (containing interleukin 2) during the culture. Reconstituted membranes made in the presence of the detergent-insoluble fraction from the plasma membrane were able to stimulate a response in the absence of Con A supernatant. |
| doi_str_mv | 10.4049/jimmunol.130.1.493 |
| format | Article |
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Membranes are shown to stimulate the generation of Moloney-specific and H-2 restricted CTL. Stimulation with solubilized, reconstituted membranes required the presence of rat lymphocyte Con A supernatant (containing interleukin 2) during the culture. 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Membranes are shown to stimulate the generation of Moloney-specific and H-2 restricted CTL. Stimulation with solubilized, reconstituted membranes required the presence of rat lymphocyte Con A supernatant (containing interleukin 2) during the culture. Reconstituted membranes made in the presence of the detergent-insoluble fraction from the plasma membrane were able to stimulate a response in the absence of Con A supernatant.</description><subject>Animals</subject><subject>Cell Membrane - immunology</subject><subject>Cell Transformation, Viral</subject><subject>Female</subject><subject>Immunologic Memory</subject><subject>Interleukin-2 - immunology</subject><subject>Mice</subject><subject>Moloney murine leukemia virus</subject><subject>Sarcoma, Experimental - immunology</subject><subject>Solubility</subject><subject>T-Lymphocytes, Cytotoxic - immunology</subject><issn>0022-1767</issn><issn>1550-6606</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE9r3DAQxUVpSDdpv0ChoFNv3oxkWWsf25B_sCGH3eRUELI17ipI1taSMfvto5BtchqYee_NzI-Q7wyWAkRz8Wy9n4bglqyEJVuKpvxEFqyqoJAS5GeyAOC8YCu5-kLOYnwGAAlcnJLTPAfWiAX5s0nWT04nGwYaehqxC4PR44HqIdnifvNEu0MK7pBsR7fUHfx-F3IHI51t2tH73-uC0_HVFZNNU0JDPfp21APGr-Sk1y7it2M9J4_XV9vL22L9cHN3-WtddLyuy0KYDpnsNcMWe10h1lVdQiPMSsqmbSrWimaFUCFwU-uy72QeGa4NGMnKvinPyc-33P0Y_k0Yk_I2duhcPiJMUdVQioqzKgv5m7AbQ4wj9mo_Wp-_VQzUK1L1H6nKSBVTGWk2_TimT61H8245MvzYvrN_d7MdUUWvnctqpuZ5_gh6AXMOgvM</recordid><startdate>19830101</startdate><enddate>19830101</enddate><creator>Duprez, V</creator><creator>Mescher, MF</creator><creator>Burakoff, SJ</creator><general>Am Assoc Immnol</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19830101</creationdate><title>Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes</title><author>Duprez, V ; Mescher, MF ; Burakoff, SJ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2883-4dce16fa1ebefa5ee8583094d7669b951b497e05e02d8a3fc64d7d2ad0d613f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Animals</topic><topic>Cell Membrane - immunology</topic><topic>Cell Transformation, Viral</topic><topic>Female</topic><topic>Immunologic Memory</topic><topic>Interleukin-2 - immunology</topic><topic>Mice</topic><topic>Moloney murine leukemia virus</topic><topic>Sarcoma, Experimental - immunology</topic><topic>Solubility</topic><topic>T-Lymphocytes, Cytotoxic - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Duprez, V</creatorcontrib><creatorcontrib>Mescher, MF</creatorcontrib><creatorcontrib>Burakoff, SJ</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of immunology (1950)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Duprez, V</au><au>Mescher, MF</au><au>Burakoff, SJ</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes</atitle><jtitle>The Journal of immunology (1950)</jtitle><addtitle>J Immunol</addtitle><date>1983-01-01</date><risdate>1983</risdate><volume>130</volume><issue>1</issue><spage>493</spage><epage>495</epage><pages>493-495</pages><issn>0022-1767</issn><eissn>1550-6606</eissn><abstract>Membranes and solubilized, reconstituted membranes from Moloney-infected tumors MBL-2 have been used to stimulate in vitro secondary cytolytic T lymphocytes (CTL) in C57BL/6 mice primed and Moloney murine sarcoma virus. 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| identifier | ISSN: 0022-1767 |
| ispartof | The Journal of immunology (1950), 1983-01, Vol.130 (1), p.493-495 |
| issn | 0022-1767 1550-6606 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80345215 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Cell Membrane - immunology Cell Transformation, Viral Female Immunologic Memory Interleukin-2 - immunology Mice Moloney murine leukemia virus Sarcoma, Experimental - immunology Solubility T-Lymphocytes, Cytotoxic - immunology |
| title | Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes |
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