Ca2+/CALMODULIN-DEPENDENT PHOSPHOLAMBAN KINASE FROM CARDIAC SARCOPLASMIC RETICULUM IS DISTINCT FROM PHOSPHORYLASE KINASE AND FORMS A REGULATORY COMPLEX WITH PHOSPHOLAMBAN AND THE Ca2+-ATPase

We recently reported that phospholamban, the activator of the cardiac sarcoplasmic reticulum calcium pump, is phosphorylated by both cAMP-dependent protein kinase and a membrane-bound, Ca2+/calmodulin-dependent phospholamban kinase. Phospholamban kinase and glycogen phosphorylase b kinase share the...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 1982-12, Vol.402 (1), p.549-557
Hauptverfasser:	Peuch, Christian J. Le, Peuch, Danielle A.-M. Le, Demaille, Jacques G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Animals Calcium - pharmacology Calcium-Binding Proteins - metabolism Calcium-Binding Proteins - pharmacology Calcium-Transporting ATPases - metabolism Calmodulin - pharmacology Dogs Fluphenazine - pharmacology Kinetics Multienzyme Complexes - metabolism Myocardium - enzymology Phosphorylase Kinase - metabolism Phosphorylation Protein Kinases - isolation & purification Protein Kinases - metabolism Sarcoplasmic Reticulum - enzymology
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