Long-term potentiation in rat hippocampus is inhibited by low concentrations of ethanol

Acute ethanol ingestion impairs memory in humans at concentrations associated with mild intoxication. A possible neurophysiological correlate of this effect is the suppression by ethanol of long-term potentiation (LTP), a persistent increase in synaptic efficiency which has been proposed as a substr...

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Veröffentlicht in:	Brain research 1990-12, Vol.537 (1), p.203-208
Hauptverfasser:	Blitzer, Robert D., Gil, Orlando, Landau, Emmanuel M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Animals Biological and medical sciences Electric Stimulation Ethanol Ethanol - pharmacology Evoked Potentials - drug effects Female gamma-Aminobutyric Acid - pharmacology Glutamate Hippocampus Hippocampus - drug effects Hippocampus - physiology In Vitro Techniques Long-term potentiation Medical sciences Membranes - physiology Microelectrodes N-methyl- d-aspartate N-Methylaspartate - physiology Rat Rats Rats, Inbred Strains Receptors, N-Methyl-D-Aspartate - drug effects Synapses - drug effects Synaptic plasticity Toxicology
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